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YAP的生物学功能及其与卵巢癌相关性研究进展 被引量:2

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摘要 Hippo-YAP信号通路是一个调控细胞增殖和凋亡的信号传导通路。YAP是该通路的主要效应分子,在保证胚胎正常生长发育、控制器官体积、维持内环境稳态中起到重要作用。同时,YAP基因也被认为是一种原癌基因,YAP表达异常与肿瘤的发生、发展密切相关。本文主要综述了YAP的生物学功能及其与卵巢癌的相关性研究。
作者 吴丹 王建东
出处 《癌症进展》 2017年第8期851-853,共3页 Oncology Progress
关键词 HIPPO YAP 卵巢癌
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