个体化目标营养管理对肿瘤化疗患者营养状况及生活质量的影响

Effects of individualized nutritional management on nutritional status and quality of life in cancer patients treated with chemotherapy

目的探讨个体化目标营养管理对肿瘤化疗患者营养状况及生活质量的影响。方法选取128例行化疗辅助治疗的恶性肿瘤患者,根据随机数字表法将患者分为观察组(n=64)及对照组(n=64),对照组患者化疗期间行常规性饮食指导,观察组患者化疗期间实施个体化目标营养管理,比较两组患者干预前后营养状况及生活质量的变化,同时记录两组患者化疗期间不良反应发生情况。结果观察组患者干预后白蛋白、转铁蛋白、血红蛋白及淋巴细胞水平高于对照组(P﹤0.05)。观察组患者干预后心理维度、生理维度、社会适应性及生活质量总评分均高于对照组(P﹤0.01)。观察组患者血液系统、胃肠系统、骨髓抑制、肝损伤不良反应发生情况均低于对照组(P﹤0.05)。结论个体化目标营养管理能有效改善患者营养状况,降低患者化疗期间不良反应,提高患者生活质量。

Objective To explore the effect of individualized nutrition management on the nutritional status and quality of life in cancer patients treated with chemotherapy. Method 128 cases of patients with malignant neoplasms treated with chemotherapy were enrolled in the study, and were randomized as study group（n=64） and control group（n=64） according to a random number table. The patients in control group were guided with routine chemotherapy diet, and the patients in study group were additionally administered with individualized nutritional management. The intervention of nutritional status and quality of life of the two groups before and after the intervention were compared, besides, the adverse reactions were recorded. Result The levels of albumin, transferrin and hemoglobin in study group were higher than those in control group（P〈0.05）. The scores of psychological latitude, physiological latitude, social adaptability and quality of life of study group were higher compared to control group（P〈0.01）. The incidence of hematological, and gastrointestinal adverse reactions, myelosuppression and liver injury of study group were lower than that in control group（P〈0.05）. Conclusion Individualized nutritional management can effectively improve the nutritional status, reduce the incidence of adverse reactions during chemotherapy and improve the quality of life of patients.