阿奇霉素联合羧甲司坦治疗急性气管-支气管炎的临床研究

Clinical study of Azithromycin combined with Carbocisteine in the treatment of acute tracheo-bronchitis

目的研究阿奇霉素联合羧甲司坦治疗急性气管-支气管炎的效果。方法选取2016年6月~2017年6月在我院接受治疗的急性气管-支气管炎患者74例,采用抽签法将患者分为对照组、研究组,每组37例。对照组采用阿奇霉素治疗,研究组采用阿奇霉素联合羧甲司坦治疗。比较两组临床症状的持续时间、不良反应发生情况及疗效。结果研究组临床症状的持续时间短于对照组,总有效率(94.6%)高于对照组(75.7%),差异有统计学意义(P<0.05)。两组治疗时的不良反应发生率差异无统计学意义(P>0.05)。结论阿奇霉素联合羧甲司坦治疗急性气管-支气管炎的临床效果显著,能够缩短患者的临床症状持续时间,改善症状,无严重的不良反应,具有应用价值。

Objective To study the effect of Azithromycin combined with Carbocisteine in the treatment of acute tracheo-bronchitis.Methods 74 patients with acute trachea-bronchialitis treated in our hospital from June 2016 to June 2017 were selected and they were divided into the control group （n=37） and research group （n=37） by drawing lots.In the control group,Azithromycin was used,while in the research group,Azithromycin combined with Carbocisteine was adopted.The duration of clinical symptoms,the occurrence of adverse reactions,and curative effect between the two groups were compared.Results In the research group,duration of clinical symptoms was shorter than that in the control group,and the total effective rate was 94.6% in the research group,which was higher than that in the control group （75.7%）,and there was a statistical difference （P〈0.05）.There was no statistical difference in the incidence of adverse reactions between the two groups （P〉0.05）.Conclusion Azithromycin combined with Carbocisteine t acute tracheobronchitis has a significant clinical effect and can shorten the duration of clinical symptoms for patients,improve syruptoms without serious adverse reactions,which has a value application