不同剂量补佳乐用于宫腔粘连术后子宫内膜修复的疗效观察

Curative effect observation of different dose Progynova applied in for endometrial repair after intrauterine adhesion operation

目的观察不同剂量补佳乐用于宫腔粘连术后子宫内膜修复的疗效。方法选取我院2015年10月12日~2016年3月20日收治的174例宫腔粘连术后子宫内膜修复患者,将其分为三组,每组58例。2 mg组给予2 mg补佳乐治疗,4 mg组给予4 mg补佳乐治疗,6 mg组给予6 mg补佳乐治疗。比较三组患者治疗后的住院时间、症状改善时间、住院费用、不良反应发生率。结果 4 mg组患者治疗后的住院时间[(15.01±0.45)d]、症状改善时间[(8.45±1.29)d]、住院费用[(3565.11±127.48)元]均优于2 mg组[(21.25±1.47)d、(10.28±2.11)d、(5627.49±159.28)元],6 mg组[(18.45±1.25)d、(9.24±0.28)d、(4252.45±145.11)元](P<0.05);4的mg组不良反应发生率为6.90%,低于2 mg组(20.90%)、6 mg组(12.07%)(P<0.05)。结论通过对宫腔粘连术后子宫内膜修复患者使用4 mg补佳乐治疗,取得十分显著的效果。

Objective To observe the curative effect of different dose Progynova applied in for endometrial repair after intrauterine adhesion operation.Methods 174 patients with endometrial repair after intrauterine adhesion treated in our hospital from October 12,2015 to March 20,2016 were selected.The patients were divided into the three groups,and there were 58 cases in each group.2 nag group was given 2 mg Progynova for treatment,4 mg group was given 4 mg Progynova for treatment,and 6 mg was given 6 mg Progynova for treatment.The hospital stay,symptom improvement time, hospitalization cost,and incidence of adverse reactions were compared among the three groups.Results The hospital stay, symptom improvement time,and hospitalization cost after therapy in 4 mg group was （15.01±0.45） d,（8.45±129） d,（3565.11± 127.48） yuan respectively,which were better than those in 2 mg group [（21.25±1.47） d,（10.28±2.11） d,and （5627.49± 159.28） yuan],and 6 mg group [（18.45±1.25） d,（9.24±0.28） d,（4252.45±145.11） yuan] （P〈0.05）.The incidence of adverse reactions in 4 mg group was 6.90%,which was lower than that of the 2 rag group （20.90%） and the 6 nag group （12.07%） （P〈0.05）.Conclusion For endometrial repair patients after intrauterine adhesion,application of 4 mg Progynova can obtain a remarkable effect.