CT增强扫描对良恶性胰腺无功能性神经内分泌肿瘤的鉴别诊断价值

Value of contrast-enhanced CT in differential diagnosis of benign and malignant non-functioning pancreatic neuroendocrine tumors

目的 :探讨CT增强扫描在良恶性胰腺无功能性神经内分泌肿瘤(NF-p NETs)鉴别诊断中的价值。方法 :回顾性分析23例经临床病理证实为NF-p NETs的CT资料,比较良恶性NF-p NETs相关CT征象的差异。结果 :恶性组病变平均直径(6.2±1.8)cm,良性组病变平均直径(4.5±1.5)cm,2组差异有统计学意义(P=0.024)。NF-p NETs中,11个病变具有侵袭性,其中良性组3个,恶性组8个,2组差异有统计学意义(P=0.012)。2组动脉期及门脉期肿瘤绝对强化值差异均有统计学意义(均P<0.05)。结论:动脉期及门脉期肿瘤绝对强化值可作为除病变大小、侵袭性外鉴别NF-p NETs良恶性的有价值的指标。

Objective：To investigate the value of contrast-enhanced CT in differential diagnosis of benign and malignant non-functioning pancreatic neuroendocrine tumors（NF-p NETs）. Methods：23 cases with single lesions pathological confirmed as NF-p NETS,were divided into the benign and malignant group. CT features of the two groups were compared. Results：There were statistically significant differences between benign and malignant group in tumor size（P=0.024） and infiltration（P=0.012）.Contrast-enhanced images showed significant differences between two groups in the absolute enhancement at the arterial and portal venous phase（all P〈0.05）. Conclusion：The absolute enhancement at the arterial and portal venous phase may provide useful information to preoperative differential diagnosis of benign and malignant NF-p NETs.