交感神经皮肤反应在躯体化障碍患者中的应用

Application of sympathetic skin response in patients with somatic disorders

目的探讨交感神经皮肤反应在躯体化障碍患者中的临床应用价值。方法选取门诊就诊和住院的躯体化障碍患者174例为躯体化障碍组,174例健康者为对照组,以交感神经反应(SSR)作为测评手段,通过交感神经的通路变化反映自主神经的状况,测量SSR起始波潜伏期和波幅。结果躯体化障碍组的起始潜伏期高于健康对照组,躯体化障碍组的波幅低于健康对照组,两组之间比较,均差异有统计学意义(均P<0.01)。结论交感神经皮肤反应测定过程中,躯体化障碍患者的起始潜伏期延长,波幅降低,能较好地反映自主神经功能紊乱,对诊断与疗效有重要的参考价值。

Objective To explore the clinical application value of sympathetic skin response( SSR) in patients with somati disorder. Methods One hundred seventy-four patients with somatization disorder were selected from our hospital department of neurology,gastroenterology,and cardiology as somatization disorder group,and 174 healthy persons were selected as control group. The latency and amplitude of the initial wave of SSR were measured and the autonomic nervous system was reflected by the change of sympathetic pathway by SSR evaluation mean. SPSS 13. 0 software was used to analyze the data statistically. Results The onset latency of somatization disorder group was higher than the control group,and the amplitude of somatization disorder group was lower than the control group,there was statistically significant difference between the two groups( P < 0. 01). Conclusion In the process of sympathetic skin response test,the onset latency of the patients with somatization disorder was prolonged and the amplitude was decreased,it could reflect the dysfunction of autonomic nervous system.