大脑中动脉远端分支高信号征对于大脑中动脉区急性脑梗死的临床意义

Clinical significance of distal middle cerebral artery hyperintensity in the acute middle cerebral artery infarction

目的回顾性研究磁共振液体衰减反转恢复(FLAIR)序列大脑中动脉远端分支高信号征(FVH)在急性大脑中动脉区脑梗死中的临床意义。方法收集首发大脑中动脉区急性脑梗死患者99例。均予以头颅MRI检查,包括磁共振弥散加权像(DWI)、T1加权像、T2加权像和FLAIR序列。分析研究磁共振FLAIR序列大脑中动脉远端分支高信号(FVH)在急性大脑中动脉区脑梗死患者中的临床意义。结果有、无FVH的急性大脑中动脉区脑梗死患者在性别、年龄、高血压、糖尿病、高脂血症、吸烟方面差异无统计学意义(P>0.05)。有FVH组和无FVH组在临床病情严重程度方面差异有统计学意义(P=0.029),而在经过治疗出院时两组NIHSS评分差异无统计学意义(P=0.062)。结论在急性大脑中动脉区脑梗死患者中远端FVH的存在预示着患者发病严重程度较高,但有利于患者短期神经功能恢复。

Objective To study retrospectively the clinical significance of MRI fluid attenuated inversion recovery( FLAIR) sequences distal middle cerebral artery vascular hyperintensity( FVH) in patients with acute middle cerebral artery infarction. Methods 99 cases of patients with acute middle cerebral artery infarction for the first time were collected. All of them were examined by cranial MRI,including MR diffusion weighted imaging( DWI),T1 weighted images,T2 weighted images and fluid attenuated inversion recovery( FLAIR) sequences. Results There were no significant difference in gender,age,hypertension,diabetes,hyperlipidemia and smoking between FVH group and non FVH group of the patients with acute middle cerebral artery infarction( P > 0. 05). There was significant difference in the severity of clinical significant disease between FVH group and non FVH group( P < 0. 05). Conclusion There is a significant correlation between FVH and clinical severity in patients with acute middle cerebral artery infarction,which has positive clinical significance for the improvement of short-term neurological function.