宫颈超薄液基细胞学检查联合HPV检测对宫颈癌前病变筛查的临床意义

Clinical significance of cervical ultrathin liquid based cytology combinedhPV screening beforedetection of cervical cancer pathological changes

目的探究宫颈超薄液基细胞学检查联合HPV检测在宫颈癌前病变筛查中的临床意义。方法选取我院接受检查的已婚患者90例作为研究对象,分别采用不同的检测方法将其分为三组,分别为实验1组(n=30),实验2组(n=30),实验3组(n=30),实验1组采用宫颈超薄液基细胞学进行检查,实验2组采用HPV检测,实验3组采用宫颈超薄液基细胞学检查联合HPV进行检测,比较三组检测方法的检测结果。结果实验1组和实验2组的病变检出率比较差异无统计学意义(P>0.05),实验3组的检出率均明显高于实验1组和实验2组,差异有统计学意义(P<0.05)。实验1组、实验2组、实验3组之间的检测出阳性合并感染情况结果比较,差异无统计学意义(P>0.05);实验3组的阳性合并感染情况高于实验1组,差异有统计学意义(P<0.05)。结论采用宫颈超薄液基细胞学检查联合HPV检测在宫颈癌前病变筛查中具有重要意义,可有效提高宫颈癌前病变患者的检出率,为该病患者的临床诊断提供较为有力的科学证据。

Objective To explore the cervical ultrathin liquid based cytology combined clinical significance ofh PVdetection in front of the cervical lesion screening. Methods Select 90 cases examined by our married patients as the research object,Usingdifferentdetection methods will bedivided into threegroups,divided into threegroups, respectively, the experimentalgroup（n = 30）, experimentalgroup（n = 30） 2, experiment 3groups（n = 30）, experimentgroup 1 with cervical ultrathin liquid based cytology, experiment withh PVdetection of twogroups, experimentalgroup 3 with cervical ultrathin liquid based cytology combinedh PV, threegroups of test results anddetection rate. Results Experiment 1 and experiment 2groupdetection rate comparison, there was not statistically significantdifference（P 0.05）, thedetection rate of experiment 3group were significantlyhigher than the experiment 1 and experiment 2group（P 0.05）. experiment 1 and experiment 2group, experiment 3groups of test results, there was not statistically significantdifference（P 0.05）; Experiment 3groups of test results washigher than experimentalgroup 1（P 0.05）.Conclusion The cervical thin liquid based cytology combinedh PVdetection is ofgreat significance in screening cervical cancer lesion before, could improvedetectable rate of cervical cancer lesion before, to provide patients with thediseasediagnosis evidence.