浅谈HPV检测及其分型在宫颈疾病中临床应用价值

Discussion on clinical application of HPV detection and typing in cervical diseases

目的分析HPV检测及其分型在宫颈疾病中临床应用价值。方法随机选取2016年1月-2016年10月的46例宫颈疾病患者,均给予HPV分型检测,对比分析检测结果。结果 25例宫颈炎患者,9例HPV呈阳性,阳性率为36%。5例CINⅠ患者,2例HPV呈阳性,阳性率为40%。4例CINⅡ患者,2例HPV呈阳性,阳性率为50%。7例CINⅢ患者,4例HPV呈阳性,阳性率为57.1%。5例宫颈癌患者,4例HPV呈阳性,阳性率为80%。就HPV呈阳性的患者而言,针对宫颈炎,7例单重感染,2例多重感染,针对CINⅠ,1例单重感染,1例多重感染,针对CINⅡ,1例单重感染,1例多重感染,针对CINⅢ,2例单重感染,2例多重感染,针对宫颈癌,3例单重感染,1例多重感染。结论 HPV分型检测可辅助诊断及筛查宫颈病变,临床应用价值高,值得广泛推广。

Objective To analyze the clinical value of HPV detection and classification in cervical diseases. Methods Randomly selected 46 cases of patients with cervical disease in January 2016-2016, were given HPV typing test, comparative analysis of test results. Results 25 cases of cervicitis patients, HPV positive in 9 cases, the positive rate was 36%. 5 CIN patients were positive for HPV, and the positive rate was in 2 cases. 4 CIN patients were positive for HPV, and the positive rate was in 2 cases. 7 patients with CIN Ⅲ were positive for HPV, and the positive rate was in 4 cases. 5 cases of cervical cancer patients, HPV positive in 4 cases, the positive rate was 80%. HPV positive patients, according to the 7 cases of cervicitis, 2 cases of single infection and multiple infections, according to CINⅠ, 1 cases of infection, 1 cases of multiple infections, according to CINⅡ, 1 cases of single infection, 1 cases of multiple infections, according to CIN Ⅲ, 2 cases of single infection in 2 cases multiple infections, for cervical cancer, 3 cases of single infection and multiple infection in 1 cases. Conclusion HPV classification can be used to assist in the diagnosis and screening of cervical lesions.