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妊娠甲状腺功能减退症孕妇基于促甲状腺素水平调整左甲状腺素剂量变化规律观察

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摘要 目的观察妊娠甲状腺功能减退症(HT)孕妇基于促甲状腺素水平调整左甲状腺素(L-T4)剂量变化规律。方法选择50例妊娠甲状腺功能减退症孕妇为研究对象,将其中23例存在妊娠前合并甲状腺功能减退孕妇设为分析组,其余27例未合并合并甲状腺功能减退孕妇设为对照组,总结对比两组治疗期间药物剂量调整对甲状腺功能指标的影响。结果分析组孕妇在妊娠3、6、9个月中,L-T4使用剂量出现明显增加,差异有统计学意义(P<0.05),对照组则各时间段,差异无统计学意义(P>0.05),说明分析组孕妇在同等妊娠月份下对L-T4剂量需求明显高于对照组,差异有统计学意义(P<0.05)。结论妊娠甲状腺功能减退症孕妇应给予早期明确诊断,对存在合并的HT孕妇应遵医嘱与相关治疗用药指南调整L-T4的剂量,以此保证孕妇妊娠早期甲状腺功能达标。
出处 《实用妇科内分泌电子杂志》 2017年第26期85-86,共2页 Electronic Journal of Practical Gynecological Endocrinology
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