纯镁含锌微弧氧化生物涂层的临床应用可行性研究

Feasibility study on the clinical application of pure magnesium zinc containing microarc oxidation biological coating

镁基金属材料具有生物可降解性和极其良好的生物活性。在纯镁金属表面通过超声微弧氧化、碱热处理以及镀锌技术制备表面含锌生物涂层,综合了超声微弧氧化技术及金属锌的生物学作用和抗菌作用,提高纯镁表面的抗菌性,即可缓解镁基材料降解过快又可预防植入前期的感染问题。开发抗菌性良好、生物活性及降解速度可人为调控的新型医用镁合金骨内固定材料具有很大的临床应用价值。本文评述了医用镁合金的研究历史、优势与现存的问题,超声微弧氧化技术的优点与锌元素特性,为纯镁含锌微弧氧化生物涂层应用于临床的理论可行性提供参考依据。

Magnesium based metal materials have biodegradability and extremely good biological activity.The surface Zn coating was prepared on the surface of pure magnesium by ultrasonic micro arc oxidation, alkali heat treatment and zinc plating,it combined ultrasonic micro arc oxidation technology with zinc metal of biological function and antibacterial actionand improving the surface antibacterial property of pure magnesium,alleviating the degradation of magnesium based materials and prevent the infection in the early stage of implantation.It is of great clinical value to develop a new type of medical magnesium alloy bone internal fixation material with good antibacterial activity, biological activity and degradation speed regulated.This paper reviews the research history, advantages and existing problems of magnesium alloy, zinc element advantages and characteristics of micro arc oxidation technology of ultrasonic and then providing reference basis for clinical feasibility of micro arc oxidation coating of zinc in pure magnesium.