替普瑞酮联合雷贝拉唑三联疗法治疗Hp感染相关性老年消化性溃疡的效果观察

For joint ray pury ketone triple therapy (Hp) treatment effect observation of infection-related elderly peptic ulcer

目的探讨替普瑞酮联合雷贝拉唑三联疗法治疗Hp(幽门螺杆菌)感染相关性老年消化性溃疡的效果。方法选择商丘市第一人民医院消化内科2015年3月-2016年7月收治的Hp感染相关性老年消化性溃疡患者60例为研究对象,随机将其分为观察组和对照组,各30例。给予观察组雷贝拉唑三联疗法联合替普瑞酮治疗,对照组给予雷贝拉唑三联疗法治疗。比较两组停药4周后溃疡愈合疗效及Hp根除率。结果观察组溃疡愈合疗效优于对照组,差异有统计学意义(P<0.05);观察组Hp根除率高于对照组,差异有统计学意义(P<0.05)。结论给予Hp感染相关性老年消化性溃疡患者替普瑞酮联合雷贝拉唑三联疗法疗效显著,可促进溃疡面快速愈合,提高Hp根除率,临床应用价值较高。

Objective To study the joint for pury ketone rabeprazole triple therapy(Hp) treatment of elderly peptic ulcer(helicobacter pylori) infection correlation effect. Methods Shangqiu first people's hospital of digestive internal medicine in March 2015-July 2016 admitted during the period of correlation between Hp infection in elderly patients with peptic ulcer 60 cases as the research object,its randomly divided into observation group and control group,30 cases each. Given observer group rabeprazole azole pury methadone treatment for triple therapy in combination with the control group given rabeprazole triple therapy treatment. Compare two groups of 4 weeks after drug withdrawal ulcer healing efficacy and Hp eradicate rate. Results The ulcer healing effect of observation group is better than that of control group,significant difference(P < 0.05); Observation group Hp eradicate rate is higher than the control group,significant difference(P < 0.05). Conclusion Gives the correlation between Hp infection in elderly patients with peptic ulcer for pury ketone joint ray triple therapy(effectiveness) treatment,can promote healing of ulcer surface rapidly improve Hp eradicate rate,higher clinical value.