摘要
采用喷雾干燥法制备胶原蛋白/壳聚糖复合微球,用纳米喷枪将复合微球的乙醇溶液均匀喷洒于粘胶纤维面膜上,制备了一种新型的含胶原蛋白/壳聚糖微球保湿面膜,并研究复合微球和面膜的形貌,面膜的保湿、透湿以及生物相容性。结果表明:喷雾干燥法制备的复合微球大小较为均一,形貌完整,含胶原蛋白/壳聚糖微球的面膜保湿率为85.3%,透湿率为4 300g·M^(-2)·h^(-1),细胞活性测试第七天仍有0.98,细胞活性大于0.8,表明该胶原蛋白;壳聚糖微球保湿面膜具有良好的生物相容性。
Collagen/chitosan composite microspheres were firstly prepared by spray drying process,and then sprayed on viscose fibermask. In this study,a novel facial mask coated by collagen/chitosan composite microspheres was prepared and its performance was studied. The results showed that the moisture-retention capacity, moisture-penetrability of this novel facial mask were 85. 3% ,4 300g ·M^-2·h^-1 Respectively. The cell activity test showed that the cell activity was 0. 98 at the 7th day of incubation, which was greater than 0 . 8 , indicating the prepared facial mask had good biocompatibility.
出处
《化学研究与应用》
CSCD
北大核心
2017年第11期1765-1768,共4页
Chemical Research and Application
基金
上海市自然科学基金项目(14ZR1401300)资助
上海市浦江人才计划项目(16PJD007)资助
国家级大学生创新训练计划项目[批准号:贵大(国)创字2016(005)]资助
关键词
喷雾干燥
胶原蛋白
壳聚糖
微球
保湿面膜
spray drying
collagen
chitosan
microspheres
facial moisturizing mask
