摘要
丁基苯酞具有多种药理作用,可治疗缺血性脑卒中明显减少梗塞后神经功能缺失、改善患者生活能力状态。近年来,国内外大量研究报道丁基苯酞的其它药理学活性,包括中枢神经系统、心血管系统、糖尿病并发症、高血压并发症等广泛药理作用。本文就近年来丁基苯酞的药理作用的研究进展做一综述,以期为丁基苯酞的深入研究和临床应用方向提供参考。
The dl-3-n-butylphthalide（ NBP） exerts a variety of pharmacological effects, and is able to significantly reduce the neurological function after infarction,improve the patient＇ s ability to live. In recent years, a large number of studies have reported the pharmacological activities of NBP,including the central nervous system,cardiovascular system, diabetic complications, complications of hypertension and other pharmacological effects. In this paper,the recent progress in the research on the pharmacological effects of NBP is briefly reviewed,and pharmacological effects of NBP and theoretical evidences for research and clinical application direction of NBP areprovided.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2017年第21期2192-2195,共4页
The Chinese Journal of Clinical Pharmacology
基金
国家自然科学基金资助项目(81560584)
关键词
丁基苯酞
药理作用
中枢神经系统
心血管系统
糖尿病并发症
高血压并发症
dl-3nervous system
hypertension- n - butylphthalide
pharmacological action
central cardiovascular system
diabetic complication
complication
