自拟前列腺炎方保留灌肠治疗52例慢性非细菌性前列腺炎临床观察

Clinical Observation of Using Self-made Prostatitis Retention Enema in the Treatment of 52 Cases of Chronic Non-bacterial Prostatitis

目的:观察自拟中药"前列腺炎方"保留灌肠治疗慢性非细菌性前列腺炎疗效。方法:随机选取2010~2015年期间门诊就诊慢性非细菌性前列腺炎患者,其中52例采用自拟中药"前列腺炎方"+西药山莨菪碱药物保留灌肠治疗;同时随机选取30例对照组,采用口服利君沙+热水坐浴进行治疗;统计两组患者治疗后其白介素和C反应蛋白水平表达变化情况、NIH-CPSI评分变化、临床治疗有效率及复发率进行疗效比较。结果:经治疗后,两组患者经治疗后C反应蛋白及白介素表达水平与治疗前相比均得以明显改善,P<0.05;但治疗组改善效果显著优于对照组,P<0.05;同时治疗组症状改善有效率为94.2%,高于对照组的70.0%,比较差异明显(P<0.05);且治疗组治疗有效率为88.46%,高于对照组的66.67%,比较差异明显(P<0.05);治疗组复发率为14.8%,低于对照组的57.9%,比较差异明显(P<0.05)。结论:中药"前列腺炎方"保留灌肠治疗慢性非细菌性前列腺炎安全有效、价格低廉、使用方便、副反应少,较适用于临床实际需求。

Objective： To explore the effect of herbal retention enema which made by ourselves on treating chronic abaeterialprostatitis. Methods： From 2010to 2015, 52patients of chronic abacterial prostatitis in our hospital were randomly divided intoresearch group and 30patients were allocated to controlled group. The research group received traditional Chinese herbal retentionenema which made by ourselvesand and anisodamine. The results showed that the changes of IL-C and C-reactive protein levels,the changes of NIH-CPSI score, the effective rate of clinical treatment and the recurrence rate were compared between the twogroups. Results： After treatment, the expression of C-reactive protein and interleukin in the two groups were significantly im-proved compared with those before treatment, P〈0.05. However, the improvement effect of the treatment group was significantlybetter than that of the controlled group, P〈O. 05. The effective rate was 88.46% in the treatment group and 66. 67% higherthan that in the controlled group （ P〈0.05 ）. The effective rate was 94. 2% , which was higher than that of the controlled group（ P〈O. 05 ）. The recurrence rate in the treatment group was 14. 8%, which was lower than that in the controlled group which was57. 9% （P〈O. 05）. Conclusion ： The clinical effect of herbal retention enema which made by ourselves is remarkable in treatingchronic abacterial prostatitis and it has the advantages of low price, convenient operation and little side effect, which is suitablefor clinical requirement.