对比分析头颈部鳞状细胞癌PET/CT与PET/MR特征

Comparative analysis of PET/CT and PET/MR image characteristics of head and neck squamous cell carcinoma

目的探讨头颈部鳞状细胞癌(HNSCC)的PET/CT及PET/MR特征。方法纳入未经抗肿瘤治疗的头颈部鳞状细胞癌患者40例,所有患者均接受PET/CT及头颈部MR检查。由2名观察者独立观察PET阳性病灶,包括阳性原发灶及阳性淋巴结;并对PET/CT、PET/MR T1WI及PET/MR T2WI的图像质量、融合准确度、病灶清晰度、病灶特征等进行评分。分析2名观察者间的一致性。结果 40例患者共90个PET阳性病灶,包括阳性原发灶40个、阳性淋巴结50个。PET/CT、PET/MR T1WI及PET/MR T2WI在图像质量及融合准确度方面差异均无统计学意义(P均>0.05);在显示阳性原发灶及阳性淋巴结的清晰度方面,PET/MR T1WI及PET/MR T2WI均优于PET/CT(P均<0.05)。40个阳性原发灶中,PET/MR T2WI对29个原发灶的特征显示多于PET/CT,4个原发灶与PET/CT相仿,7个原发灶较PET/CT少。结论 PET/MR在HNSCC诊断中的应用是可行的,在显示头颈部局部病灶时较PET/CT更具优势。

Objective To investigate PET/CT and PET/MR characteristics of head and neck squamous cell carcinoma（HNSCC）.Methods Totally 40 patients with HNSCC underwent whole body 18 F-FDG PET/CT and MR scans of head and neck before anti-tumor treatment.PET positive lesions of HNSCC,including primary lesions and lymph nodes were evaluated by 2 radiologists independently.Then the imaging quality,fusion quality,lesion conspicuity and lesion characteristics were assessed based on PET/CT,PET/MR T1 WI and PET/MR T2 WI.Results Ninety PET positive lesions in all 40 patients were evaluated,including 40 primary lesions and 50 lymph nodes.Similar imaging quality and fusion quality of PET/CT,PET/MR T1 WI and PET/MR T2 WI were obtained without statistical difference（both P0.05）.For the lesion conspicuity,PET/MR T1 WI and PET/MR T2 WI demonstrated significantly better than PET/CT in positive primary lesions and lymph nodes（all P0.05）.For the characteristics of positive primary lesions,PET/MR T2 WI provided more information than PET/CT in 29 lesions,equal to PET/CT in 4 lesions,and less than PET/CT in 7 lesions.Conclusion The application of PET/MR in HNSCC is feasible,being superior to PET/CT in indication of lesions in head and neck area.