婴儿纤维性错构瘤CT、MRI特征与组织病理学对照分析

CT and MRI features of fibrous hamartoma of infancy:Comparison with histopathology

目的探讨婴儿纤维性错构瘤(FHI)的CT、MRI表现并与病理对照。方法回顾性分析经手术病理证实的15例FHI患儿的临床、CT、MRI及病理学资料。结果 15例FHI中,单灶13例、双灶2例,共17个病灶,CT、MRI表现为皮下型、皮肤型和混合型病灶分别占58.82%(10/17)、17.65%(3/17)和23.53%(4/17)。皮下型、混合型病灶呈"云雾征"(包括"淡云征"及"浓云征"),其中"淡云征"病灶以成熟脂肪细胞为主,"浓云征"病灶的成熟脂肪细胞、致密纤维细胞及原始间叶细胞三相成分构成比较一致。皮肤型病灶呈"倒峦征",以原始间叶细胞为主。结论 FHI的CT、MRI表现复杂但也有一定的特点,可较好地反映其组织病理学特性。

Objective To discuss CT,MRI features of fibrous hamartoma of infancy（FHI）compared with pathology.Methods Cinical data,CT and MRI findings,as well as pathological results of 15 patients with FHI were retrospectively analyzed.Results Totally,there were 17 lesions of FHI in 15 cases,including 13 cases with single lesion and 2 cases with double lesions.The lesions manifesting as subcutaneous-,skin-and mixed-type on CT or MR images accounted for58.82%（10/17）,17.65%（3/17）and 23.53%（4/17）,respectively.The subcutaneous-and mixed-type lesions showed ＂cloud sign＂（including ＂thin-cloud sign＂ and ＂thick-cloud sign＂）.The thin-cloud sign lesions composed mainly of mature adipose tissue,while the triphasic composition ratio of adipose,fibrous and primitive mesenchymal cells were relatively consistent in the lesions with thick-cloud sign.The skin-type lesions showed ＂ mountain-inverted sign＂,which composed mainly of immature mesenchymal component.Conclusion CT and MRI features of FHI are complex,yet have certain characteristics,which can preferably reflect the histopathological features of FHI.