摘要
脑老化指随着年龄增长,大脑组织结构、功能、形态逐渐出现衰退的现象,其中认知功能减退是脑老化的重要标志,脑白质的退行性改变可能是造成脑老化的重要因素。DTI及其图像处理技术能够无创显示活体人脑组织微观结构,有利于分析脑老化过程及脑老化相关疾病。本文对DTI技术在正常脑老化中的研究现状及进展做一综述。
Brain aging refers to the gradual decline of brain tissue structure,function and morphology with age.The cognitive dysfunction is an important marker of brain aging.Degenerative brain white matter changes may be an important factor in brain aging.DTI and its image processing techniques can noninvasively display the microstructure of human brain in vivo.Additionally,it is beneficial to analyze aging process of brain and related diseases of brain aging.The current status and progresses of diffusion tensor imaging in normal brain aging were reviewed in this article.
出处
《中国医学影像技术》
CSCD
北大核心
2017年第11期1716-1719,共4页
Chinese Journal of Medical Imaging Technology
基金
上海市自然科学基金(16ZR1416000)
上海健康医学院协同创新项目(HMCI-16-11-002)
关键词
扩散张量成像
脑老化
脑白质
Diffusion tensor imaging
Brain aging
White matter