功能性消化不良合并焦虑抑郁障碍的危险因素分析

Analysis of Risk Factors for Functional Dyspepsia Combined With Anxiety and Depression

目的探讨功能性消化不良(FD)患者合并焦虑抑郁障碍的危险因素。方法对2013年1月—2016年12月在我院诊断为功能性消化不良的所有患者前瞻性进行汉密尔顿焦虑量表和汉密尔顿抑郁量表评定,根据结果分为FD伴焦虑抑郁障碍组和FD不伴焦虑抑郁障碍组,观察两组危险因素。结果 FD伴焦虑抑郁障碍组患者中焦虑抑郁障碍的发病率为21%,FD伴焦虑抑郁障碍组中更多患者存在经济状况差、非腹部慢性疾病等因素,结果显示婚姻缺陷、睡眠障碍、病程长(>3年)是FD患者发生焦虑抑郁障碍的独立危险因素。结论婚姻缺陷、睡眠障碍、病程长(>3年)是FD患者合并焦虑抑郁障碍的危险因素,临床诊疗中应对伴随这些因素的FD患者进行焦虑抑郁障碍的评估。

Objective To investigate the functional dyspepsia （FD） risk factors in patients with anxiety and depression. Methods From January 2013 to December 2016, patients with functional dyspepsia in our hospital were prospectively evaluated by Hamilton anxiety scale and Hamilton depression scale, according to the results, they were divided into FD with anxiety and depression group and FD without anxiety and depression group, the risk factors of the two groups were observed. Results The incidence of anxiety and depression in FD with anxiety and depression group were 21%, there were more patient with poor economic status, non abdominal chronic diseases and other factors in FD with anxiety and depression group, the results showed that marital defects, sleep disorders, long course of disease （〉3 years） were independent risk factors of anxiety and depression in FD patients. Conclusion Defects, sleep disorders, long course of disease （〉 3 years） are the risk factors of anxiety and depression in FD patients. In clinical diagnosis and treatment, FD patients with these factors should be evaluated for anxiety and depression.