脂蛋白(a)联合胆红素检测诊断冠心病的临床价值

Clinical Value of Lipoprotein(a) Combined with Bilirubin Detection in the Diagnosis of Coronary Heart Disease

目的探讨脂蛋白(a)联合胆红素检测诊断冠心病的临床价值。方法选取我院2015年3月至2017年3月收治的54例冠心病患者作为观察组,另选取同期54名健康体检者作为对照组。采用免疫比浊增强法检测血清脂蛋白(a)水平,采用钒酸盐法检测血清胆红素水平。分析比较两组的血清脂蛋白(a)和胆红素水平。结果对照组的血清脂蛋白(a)水平明显低于观察组,差异有统计学意义(P<0.05)。对照组的血清胆红素水平显著高于观察组,差异有统计学意义(P<0.05)。结论脂蛋白(a)、胆红素水平对冠心病发生、发展均有一定的影响,两者联合检测可为冠心病诊断提供有效参考数据。

Objective To explore the clinical value of lipoprotein （a） combined with bilirubin detection in the diagnosis of coronary heart disease. Methods 54 cases of patients with coronary heart disease admitted to our hospital from March 2015 to March 2017 were selected as the observation group, and another 54 healthy people were selected as the control group. The serum lipoprotein （a） level was detected by turbidimetric immunoassay, and the serum bilirubin level was detected by vanadate method. The serum lipoprotein （a） and bilirubin levels were analyzed and compared between two groups. Results The serum lipoprotein （a） level of control group was significantly lower than that of observation group, with statistical difference （P〈0.05）. The serum bilirubin level of control group was significantly higher than that of observation group, with statistical difference （P〈0.05）. Conclusions The lipoprotein （a） and bilirubin levels have some influence on the occurrence and development of coronary heart disease. The combined detection can provide an effective reference data in the diagnosis of coronary heart disease.