富氢水对骨性关节炎中关节软骨的作用
The effect of hydrogen - rich water on cartilage in rabbit osteoarthritis models
摘要
氢有一定的治疗作用,其主要特点是抗氧化损伤、抗炎性反应和减少细胞凋亡。而氧化损伤和炎性反应与骨性关节炎(OA)发生发展密切相关,我们通过腹腔注射富氢水后观察其对OA的作用。
出处
《中华实验外科杂志》
CSCD
北大核心
2017年第11期1838-1838,共1页
Chinese Journal of Experimental Surgery
基金
海南省卫生厅重点项目(琼卫2014重点-06)
海南省高等学校科学研究项目(Hnky2015-34)
参考文献2
-
1李皓桓,孟羿彬,叶恒,柯陈荣,彭文飞.吡咯喹啉醌对兔骨关节炎模型关节软骨的保护作用[J].中华实验外科杂志,2012,29(7):1239-1241. 被引量:3
-
2程少文,应晓洲,安涛,赵志蓉,周英勇,彭磊.尼古丁对软骨细胞中炎性因子表达的影响[J].中华实验外科杂志,2015,32(3):562-562. 被引量:1
二级参考文献13
-
1李皓桓,刘世清,彭昊,徐怡,邹祖玉.吡咯喹啉醌对许旺细胞合成与分泌神经生长因子的影响[J].中华显微外科杂志,2005,28(3):242-243. 被引量:19
-
2向川,杜靖远,翁习生,卫小春.转化生长因子-β1基因和胰岛素样生长因子1基因联合转染治疗兔膝骨性关节炎的研究[J].中华实验外科杂志,2005,22(12):1540-1542. 被引量:20
-
3Kim J,Xu M, Xo R, et al. Mitochondrial DNA damage is involved inapoptosis caused by pro-inflammatory cytokines in human OA chon- drocytes. Osteoarthritis Cartilage,2010,18:424-432.
-
4Tao R, Karliner JS, Simonis U, et al. Pyrroloquinoline quinone pre- serves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes. Biochem Biophys Res Commun, 2007,363: 257- 262.
-
5Tushan FS, Rodnan GP, Altman M, et al. Anaerobic glycolysis and lactate dehydrogenase ( LDH ) isozymes in articular cartilage. J Lab Clin Med,1969,73:649-650.
-
6Grishko V, Xu M, Ho R, et al. Effects of hyaluronic acid on mitochon- drial function and mitochondria-driven apoptosis following oxidative stress in human chondrocytes. J Biol Chem,2009 ,284 :9132-9139.
-
7Blanco FJ, Rego I, Ruiz-Romero C. The role of mitochondria in osteo- arthritis. Nat Rev Rheumatol,2011,7 : 161-169.
-
8Ouchi A, Nakano M, Nagaoka S, et al. Kinetic study of the antioxi- dant activity of pyrroloquinolinequinol PQQH (2), a reduced form of pyrroloquinolinequinone] in micellar solution. J Agric Food Chem, 2009,57:450-456.
-
9Rucker R, Chowanadisai W, Nakano M. Potential physiological impor- tance of pyrroloquinoline quinone. Altern Med Rev, 2009, 14 : 268- 277.
-
10Chowanadisai W, Bauerly KA, Tchaparian E, et o.1. Pyrreloquinoline quinone stimulates mitochondrial biogenesis through cAMP response dement-binding protein phosphorylation and increased PGC-1 alpha expression. J Biol Chem,2010,285 : 142-152.
-
1张荷慧,张庆元,吴森翔,邵蓓.单唾液酸四己糖神经节苷脂钠联合依达拉奉对急性脑梗死患者血清Hcy和hs-CRP的影响[J].中国生化药物杂志,2017,37(10):144-146. 被引量:7
-
2叶艳.组胺受体拮抗剂联合白三烯受体拮抗剂治疗过敏性鼻炎的疗效观察[J].安徽医药,2017,21(11):2069-2073. 被引量:22
-
3张淑香,王秋月,王雪松,王琪,许贵军.益智膏滋对血管性痴呆大鼠脑损伤的作用研究[J].中国药师,2017,20(11):1950-1953. 被引量:2
-
4殷小杰,马晓静,王岚,贡磊磊,李丽,肖永庆,梁日欣.三黄泻心汤“炮制配伍”活血化瘀优势方抗大鼠动脉粥样硬化作用的研究[J].中国药物警戒,2017,14(9):518-522. 被引量:4