摘要
目的 :探讨99m Tc O4-/99m Tc-MIBI双核素显像检查在甲状腺结节良、恶性诊断中的应用价值。方法 :对近年来自贡市第四人民医院收治的54例甲状腺结节患者的临床资料进行回顾性研究。对这54例患者分别进行99m Tc O4-显像检查、99m Tc-MIBI显像检查和99m Tc O4-/99m TcMIBI双核素显像检查。将这三种检查结果与手术探查或针刺活检诊断结果进行比较,对比用这三种检查方法诊断甲状腺结节良、恶性的灵敏度、特异性和准确性。结果 :对54例患者进行99m Tc O4-/99m Tc-MIBI双核素显像检查的灵敏度、特异性和准确性均高于进行99m Tc-MIBI显像检查或99m Tc O4-显像检查,差异具有统计学意义(P<0.05)。对54例患者进行99m Tc-MIBI显像检查的灵敏度高于进行99m Tc O4-显像检查,对其进行99m Tc-MIBI显像检查的特异性低于进行99m Tc O4-显像检查,差异具有统计学意义(P<0.05)。对54例患者进行99m Tc-MIBI和99m Tc O4-显像检查的准确性相比差异无统计学意义(P>0.05)。结论 :对甲状腺结节患者进行99m Tc O4-/99m Tc-MIBI双核素显像检查的灵敏度、特异性及准确性均较高,可为临床上诊断甲状腺结节的良、恶性提供可靠的依据。
to discuss the clinical value of 99 mTcO4-combining 99 m Tc-MIBI radionuclide imaging on differential diagnosis of thyroid nodule and malignant lesions. Methods： 99 mTcO4-combining 99 m Tc-MIBI radionuclide imaging was conducted on 54 patients found with thyroid nodules by CT. The sensitivity, specificity, accuracy of two methods and combining application in diagnosing thyroid nodules were separately calculated, and then compared with pathological findings. Comparative analysis using statistical method was conducted on the results of combination application and single method. Results： the sensitivity of 99 mTcO4-imaging is lower than that of 99 m Tc-MIBI and specific resistance higher than that of the 99 m Tc-MIBI imaging. The difference is statistically significant, their accuracy have not significant difference; the sensitivity of two methods of 99 mTcO4-and 99 m Tc-MIBI combined imaging, specificity and accuracy are higher than 99 mTcO4-or 99 m Tc-MIBI single imaging. The differences were statistically significant.Conclusions： 99 mTcO4-combining 99 m Tc-MIBI radionuclide imaging on diagnosing thyroid nodules can complement each other＇s advantages and provide more reliable clinical evidence on diagnosing benign or malignant thyroid nodules, so it is worthy further promotion.
