淀粉样变相关脑出血手术治疗的临床疗效观察

Clinical curative effect observation of surgical treatment for amyloidosis associated cerebral hemorrhage

目的探讨淀粉样变相关脑出血手术治疗的临床疗效。方法采用外科手术治疗急性自发性淀粉样变相关颅内出血患者37例,对患者术后神经功能的恢复及预后进行观察,并随访1年。结果本组患者术后1个月时的美国卫生研究院卒中量表(NIHSS)和格拉斯哥预后量表(GOS)评分与术前比较,差异无统计学意义(均P>0.05);而术后6个月、12个月的NIHSS和GOS评分均比术前有明显改善,差异均有统计学意义(均P<0.05)。结论淀粉样变相关脑出血具有一定的临床特征,如患者有手术指征,应积极予以手术治疗,并预防术后并发症;其手术治疗的效果较好。

Objective To explore clinical curative effect of surgical operation in treating amyloidosis associated cerebral hemorrhage patients. Methods 37 patients with acute spontaneous intracranial bleeding were selected and followed up for 1 year after operation. The curative effect was analyzed retrospectively. Results 37 patients were scored by NIHSS and mRS score in preoperative and postoperative （1 m,6 m, 12 m） respectively,compared to preoperative and postoperative NIHSS and mRS score, the difference was not statistically significant （ P 〉 0.05,1 m）, the difference was statistically significant （P 〈 0. 05,6 m, 12 m ）. Conclusion Amyloidosis associated cerebral hemorrhage has certain clinical features, we should actively surgery once surgical indication is clear, surgery can reduce complications and improve patient quality of life