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组蛋白去乙酰化酶抑制药对损伤和感染性炎性反应中巨噬细胞表型的影响

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摘要 急性百草枯(Paraquat,PQ)中毒及脓毒症均为常见的急危重症。PQ是1,1’-二甲基-4,4’-联吡啶阳离子盐,一种广泛应用的快速灭生性除草剂。急性PQ中毒作为一种急性损伤,主要机制是氧化损伤。组织的氧自由基损伤刺激炎性细胞(如巨噬细胞)分泌各种炎性介质,
作者 崇巍 曾仁庆
出处 《武警医学》 CAS 2017年第9期865-868,共4页 Medical Journal of the Chinese People's Armed Police Force
基金 国家自然基金面上项目(81350120) 辽宁省自然基金面上项目(201602815) 沈阳市科技计划(F15-139-9-24)
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