军事训练致劳力性热射病对血清HSP72水平的影响

Serum HSP72 levels in military training induced exertional heat stroke patients

目的探讨军事训练致劳力性热射病(exertional heat stroke,EHS)对血清HSP72水平的影响。方法回顾性分析2012-01至2016-06共14例EHS患者HSP72水平,并与新兵、老兵和一般中暑患者比较。结果 EHS患者组血清HSP72水平(132.34±15.38)ng/ml,明显高于一般中暑患者组(62.14±9.18)ng/ml,老兵组(41.85±5.34)ng/ml和新兵组(35.52±5.16)ng/ml,差异有统计学意义,且EHS患者HSP72水平与其APACHEⅡ评分呈正相关(r=0.631,P=0.016)。结论 EHS患者血清HSP72水平检测有助于EHS诊断与病情监测。

Objective To investigate the effect of exertional heat stroke（EHS） induced by military training on levels of HSP72 of patients. Methods The HSP72 levels of fourteen EHS patients admitted between January 2012 and June 2016 were analyzed and compared with those of recruits,veterans and general heat stroke patients. Results The serum HSP72 levels of EHS patients were significantly higher than those in the general heat stroke group（62. 14 ± 9. 18） ng/ml,veterans group（41. 85 ± 5. 34） ng/ml and recruits group（35. 52 ± 5. 16） ng/ml; the difference was statistically significant（P 〈0. 001）. There were positive correlations between HSP72 levels and APACHE Ⅱ scores in EHS patients（correlation coefficient r = 0. 631,P = 0. 016）. Conclusions The detection of serum HSP72 levels in patients is conducive to diagnosis and monitoring of EHS.