长春西汀应用于脑出血开颅术后患者的临床意义研究

Study on clinical significance of vinpocetine in patients with cerebral hemorrhage after craniotomy

目的探讨长春西汀治疗脑出血开颅术后患者的临床疗效。方法 80例脑出血开颅术后患者,随机分为试验组和对照组,各40例。对照组采取常规治疗,试验组在对照组的基础上给予长春西汀进行治疗,比较两组患者临床疗效。结果两组患者手术前、术后第7天神经功能缺损评分比较差异无统计学意义(P>0.05);试验组患者出院时神经功能缺损评分为(9.13±3.12)分,优于对照组的(12.64±4.32)分,差异有统计学意义(P<0.05)。结果长春西汀治疗脑出血开颅术后患者,可以明显改善患者的神经功能缺损情况,值得临床推广。

Objective To discuss the clinical efficacy of vinpocetine in the treatment of patients with cerebral hemorrhage after craniotomy. Methods A total of 80 patients with cerebral hemorrhage after craniotomy were randomly divided into experimental group and control group, with 40 cases in each group. The control group was treated with conventional therapy, and the experimental group was treated with vinpocetine on the basis of the control group. The clinical efficacy in two groups was compared. Results Both groups had no statistically significant difference in neurological deficit score before operation and 7 d after operation（P0.05）. The experimental group had better neurological deficit score at discharge as（9.13±3.12） points than（12.64±4.32） points in the control group, and the difference was statistically significant（P0.05）. Conclusion Vinpocetine can obviously improve neurological deficit of patients with cerebral hemorrhage after craniotomy, and it is worthy of clinical promotion.