河北省2010—2013年宫颈癌发病和死亡现状及40年死亡趋势分析

Cervical cancer incidence and mortality in 2010-2013 and the mortality trend in last 40 years in Hebei Province

目的 :评估河北省2010—2013年宫颈癌发病和死亡现状,分析河北省宫颈癌40年死亡率的时间变化趋势。方法:按照全国肿瘤登记中心制定的审核方法和评价标准,对河北省肿瘤登记办公室收集的21个肿瘤登记点的恶性肿瘤数据进行审核评价,按照年龄进行分层,分别计算发病和死亡指标,以1/100 000表示。死亡数据来源于河北省3次全死因监测报告。应用Joinpoint线性回归模型计算河北省磁县和涉县宫颈癌发病率和死亡率的估计年度变化百分比(estimated annual percentage change,EAPC)。结果:河北省2010—2013年估计宫颈癌新发病例和死亡病例分别为21 942例和5 770例;粗发病率为14.62/100 000,世标发病率为10.78/100 000;粗死亡率为3.74/100 000,世标死亡率为2.69/100 000。1973—1975至2010—2013年,河北省宫颈癌死亡率呈现明显的下降趋势。1988—2001年磁县宫颈癌发病率以每年0.94%的幅度下降,随后以每年10.67%的幅度上升;死亡率EAPC为1.03;2000—2013年涉县宫颈癌发病率和死亡率的EAPC分别为7.04和3.63。结论:河北省宫颈癌的疾病负担正不断增加,应继续加强宫颈癌的防治工作。

Objective： The aim of this study burden in 201 0-2013 and analyze years in Hebei Province, China. Methods： Province from the stratified is to estimate the cervical cancer the mortality trend in the last forty Cancer registry data from 21 cancer registries in Hebei were qualified and checked according to the regulations National Cancer Registry Center. The pooled data were by age. The incidence and mortality rates were calculated and expressed in 1/100 000. Cervical cancer Hebei Province were extracted from the national annual percentage change （EAPC） for the whole was evaluated using Joinpoint regression model. mortality data during the three periods in death surveys and calculated. The estimated period in Cixian County and Shexian County Results： The estimated numbers of newly diagnosed cervical cancer cases and deaths in 2010-2013 were 21 942 and 5 770, respectively. The crude incidence rate （CIR） was 14.62/100 000; the age-standardized incidence rate using Segi＇s population standard by WHO （ASIRW） was 10.78/100 000. The crude mortality rate （CMR） was 3.74/100 000; the age-standardized mortality rate using Segi＇s population standard by WHO （ASMRW） was 2.69/100 000. The ASMRW displayed a decreasing trend in Hebei Province from 1973-1975 to 2010-2013. In Cixian county, the incidence rate decreased with an EAPC of -0.94% from 1988 to 2001. A significant increasing trend was shown from 2001 to 2013, with an EAPC of 10.67%; the mortality rate showed an increasing trend form 1988 to 2013, with an EAPC of 1.03. A similar increasing trend was observed for the incidence and mortality rates in Shexian county in 2000-2013, with EAPC of 7.04 and 3.63, respectively. Conclusion： Hebei Province experienced a relative heavy burden of cervical cancer. Effective measures should be taken to prevent and control the cervical cancer.