摘要
目的:探讨CO_2激光鼓膜手术联合加味清震汤治疗难治性分泌性中耳炎的临床疗效。方法:76例难治性分泌性中耳炎患者随机分为观察组与对照组,各38例,观察组行CO_2激光鼓膜手术联合加味清震汤治疗,对照组则给予单纯CO_2激光鼓膜手术。对两组临床疗效、不良反应、治疗前后中医证候积分、听阈、耳峰压值及静态声顺值进行比较。结果:观察组有效率92.11%显著高于对照组的73.68%(P<0.05)。与治疗前比较,治疗后两组患者听力下降、耳胀、耳鸣、耳痛证候积分及总分显著改善,听阈值显著下降,差异有统计学意义(P<0.05),且观察组治疗后上述指标均明显优于对照组(P<0.05)。观察组治疗后耳峰压值、静态声顺值与对照组比较,差异有统计学意义(P<0.05)。两组均无明显不良反应发生。结论:CO_2激光鼓膜手术联合加味清震汤治疗难治性分泌性中耳炎安全有效。
Objective： To study clinical efficacy of CO2 laser membrane surgery combined with modified Qingzhen Decoction in treatment of Refractory secretory otitis media. Methods： 76 patients with Refractorys ecretory otitis media were randomly divided into the observation group and the control group（ each 38 cases）. The observation group treated with CO2 laser membrane surgery combined with modified Qingzhen Decoction,while the control group received CO2 laser membrane surgery only. The clinical efficacy,adverse reactions,TCM symptom scores,auditory threshold,ear peak pressure and static compliance value of both groups before and after the treatment were compared. Results： The total effective rate of the observation group was 92. 11%,which was significantly higher than that（ 73. 68%） of the control group（ P〈0. 05）. Compared with those before treatment,the degrees of hearing loss,aural fullness,tinnitus,otalgia symptom scores,total symptom score,auditory threshold value in the two groups significantly decreased after treatment（ P〈0. 05）,and the above indexes in the observation group after the treatment were significantly lower than that of the control group respectively（ P〈0. 05）. There was a significant difference in ear peak pressure and static compliance value between the observation group and the control group after the treatment（ P〈0. 05）. No obvious adverse reactions occurred. Conclusion： CO2 laser membrane surgery combined with modified Qingzhen Decoction the treatment of refractory secretory otitis media is safe and effective.
出处
《中医学报》
CAS
2017年第11期2237-2239,共3页
Acta Chinese Medicine
基金
湖北省自然科学基金面上基金项目(2015CFB615)
