乳腺癌超声声像图特征对判断乳腺癌腋下淋巴结转移的临床价值

Clinical value of ultrasonographic features on estimation of axillary lymph node metastasis in breast cancer

目的:探讨乳腺癌超声声像图特征与腋下淋巴结转移的关系。方法:对2014-07~2016-10本院经超声检查和手术病理确诊的194例浸润性乳腺癌患者的临床资料进行回顾性分析,采用Spearman等级相关分析法分析超声声像图特征与腋下淋巴结转移的相关性。结果:与无腋下淋巴结转移者相比,腋下淋巴结转移者在有无边缘毛刺特征、血管指数和腋淋巴结最大皮质厚度等指标比较,差异均具有统计学意义(P<0.05)。Spearman等级相关分析结果显示腋下淋巴结转移与边缘毛刺特征(r=0.351,95%CI:0.246~0.483,P<0.05)、血管分布分级(r=0.402,95%CI:0.193~0.605,P<0.05)、腋淋巴结最大皮质厚度(r=0.636,95%CI:0.439~0.824,P<0.05)呈显著正相关。结论:乳腺癌腋下淋巴结转移在边缘、血管分布分级、皮质厚度等方面有典型的超声声像表现,有助于判断淋巴结转移的情况。

Objective：To explore the association between axillary lymph node metastasis and the ultrasonographic features in breast cancer.Methods： Clinical data of 194 patients diagnosed with breast cancer from July 2014 to October 2016 were retrospectively analyzed. Spearman rank correlation analysis was used to analyze the correlation between axillary lymph node metastasis and the ultrasonographic features. Results： Compared with those without axillary lymph node metastasis, there were significant differences in the characteristics of marginal burr, blood flow grade and maximum cortical thickness of axillary lymph nodes in axillary lymph node metastasis. Spearman rank correlation analysis showed that there were positive correlation between axillary lymph node metastasis and marginal burr （r = 0.351,95 % CI ： 0.246 --0.483,P〈0.05） ,blood flow grade （r=0.402,95%CI：0.193--0.605,P〈0.05）,the maximum cortical thickness of axillary lymph nodes （r = 0. 636, 95% CI： 0. 439 -- 0. 824, P 〈 0.05）. Conelusion：The marginal burr, blood flow grade and maximum cortical thickness of axillary lymph nodes are the most frequent ultrasonographic features of axillary metastatic lymph nodes in breast cancer patients,which could be a predictor of axillary lymph node metastasis.