食品中磺胺类药物检测方法研究进展

Research progress on detection of sulfonamides in food

磺胺类兽药残留是目前重要的动物源性食品安全问题,检测食品中磺胺类兽药残留对人体健康具有重要的意义。本文凝练了近5年食品中磺胺类药物残留检测的通用前处理方法及其原理。研究发现,食品中磺胺类药物的检测,其前处理方法具有显著共性特征。具体体现在:磺胺类药物前处理操作的原理和步骤可以在具有相同或相似基质特征的食品之间相互借鉴,得到磺胺检测方法通式,从而有助于提高检测效率。不同的前处理方法相应满足高通量、高灵敏度或操作简便等不同的检测需求。此外,本文还介绍了磺胺类药物残留检测前处理的新技术,结合实际情况分析了这些新技术的可行性,并对新技术方法与目前常用技术方法之间的灵敏度进行了比较。最后,文章对磺胺类药物残留检测技术的研究方向进行了展望。

Sulfonamides residues are important animal-derived food safety problems. It is of great significance for human health to detect the sulfonamides residues in food. First of all, the general pretreatment methods and principles of sulfonamides residues detection in food in recent 5 years were condensed. The results showed that the pretreatment methods of sulfonamides in food had obvious common characteristics. The common characteristics embodied in that general formula of sulfonamides detection methods would be possible to be made under the same or similar matrix between the characteristics of food by their principle and procedure of pretreatment operation in sulfonamides, which was helpful to improve the detection efficiency. Different pretreatment methods met different requirements such as high throughput, high sensitivity, and high efficiency, respectively. Additionally, this paper introduced new pretreatment techniques for the detection of sulfonamides, analyzed the feasibility of the new technology combined with the actual situation, and compared the advantages of sensitivity between new technology and the common technology. Finally, the research direction of sulfonamides residues detection technology was discussed.