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恩替卡韦治疗慢性乙型肝炎病毒感染患者的临床效果 被引量:1

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摘要 目的探讨恩替卡韦治疗慢性乙型肝炎病毒感染患者的临床效果。方法随机选择2015年1—12月期间收治的慢性乙型肝炎病毒感染患者68例,并将其随机分为两组,各34例。给予对照组阿德福韦酯片治疗,给予试验组恩替卡韦治疗。对治疗后两组丙氨酸转氨酶(ALT)水平、乙型肝炎病毒脱氧核糖核酸(HBV-DNA)水平、乙型肝炎E抗原(Hbe Ag)转阴率及不良反应发生情况比较分析。结果治疗后,试验组ALT水平显著低于对照组,HBV-DNA水平显著低于对照组(P<0.05);两组Hbe Ag转阴率及不良反应发生率比较,差异均无统计学意义(P>0.05)。结论对慢性乙型肝炎病毒感染患者采用恩替卡韦治疗,利于降低HBV-DNA水平和ALT水平,Hbe Ag转阴率和安全性均较理想。
作者 尹盛才
出处 《医疗装备》 2017年第21期92-93,共2页 Medical Equipment
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