不同手术介入时机治疗脑动脉瘤破裂的应用效果及并发症分析

Application of different surgical intervention time in the treatment of cerebral aneurysm rupture and its complications

目的研究不同手术时机介入手术治疗脑动脉瘤破裂的临床疗效差异,为临床提供有效依据。方法选取106例脑动脉瘤破裂患者为研究对象,根据手术时机不同进行分组。观察组53例,在动脉瘤破裂早期(发病3天内)进行介入栓塞术治疗,对照组53例则为晚期(发病3天以上)介入栓塞治疗,对两组患者疗效、术后恢复及并发症情况进行比较。结果观察组患者栓塞成功率高达94.3%,对照组患者栓塞成功率为79.2%,观察组显著优于对照组,差异具有显著性(P<0.05);观察组术后呼吸恢复开始时间为(14.3±2.8)分钟,明显低于对照组的(20.2±3.7)分钟;观察组呼唤后可睁眼时间、定向力恢复时间、离开手术室时间均短于对照组,两组比较差异具有显著性(P<0.05);观察组治疗后并发症发生率为7.6%,显著低于对照组并发症发生率41.7%,差异具有显著性(P<0.05)。结论早期介入栓塞术治疗脑动脉瘤破裂能够显著提高疗效,减少术后恢复时间及并发症的发生。

Objective To study the clinical efficacy of different surgical intervention in the treatment of cerebral aneurysm rupture and provide an effective basis for clinical. Method A total of 106 patients with cerebral aneurysm rupture from January 2013 to August 2016 in our hospital were enrolled, arid were divided into different groups ac- cording to the timing of operation. 53 patients in the observation group were treated by interventional embolization in the early stage of aneurysm rupture （53 cases in the control group）. The patients in the control group were treated with interventional embolization for non-early stage （above 3d） Recovery and complications were compared. Result The observation group of patients with embolization success rate was 94.3 % patients in the control group, the control group＇ embolization success rate was 79.2%, the observation group was significantly better than the control group, the difference was statistically significant （P〈0.05） ; the start time for the recovery of respiratory patients in the observation group （14.3±2.8） min was significantly lower than the control group （20.2±3.7） rain ;call after opening eyes time, orientation recovery time, leave the operation room time of observation group was shorter than the control group, the two groups was statistically significant（P〈0.05 ） ;the complication rate was 7.6% in the observation group after treatment, it was significantly lower than the control group（ 41.7% ）, the difference was statistically significant（ P〈0.05 ）. Conclusion Early interventional embolization for cerebral aneurysm rupture can significantly improve the curative effect, reduce the recovery time and the occurrence of complications, it is worthy of clinical application.