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背根神经节脉冲射频联合复方倍他米松注射治疗老年退行性腰椎管狭窄症的疗效观察 被引量:7

Effect of dorsal root ganglion pulsed radiofrequency combined with compound betamethasone injection in treatment of senile degenerative lumbar spinal stenosis
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摘要 目的 探讨背根神经节脉冲射频联合复方倍他米松注射治疗老年退行性腰椎管狭窄症的临床疗效.方法 收集本科室2014年12月至2015年6月收治的经保守治疗无效的老年退行性腰椎管狭窄症患者18例,均行背根神经节脉冲射频联合复方倍他米松注射治疗.记录治疗前及治疗后1 d、3 d、1周、1个月、6个月患者的疼痛视觉模拟评分(VAS)和Oswestry功能障碍指数(ODI)并进行比较.结果 18例患者均顺利完成手术,无术中及术后并发症发生.术前患者VAS评分为(6.5±0.7)分,术后1 d、3 d、1周、1个月、6个月VAS评分分别为(2.7±1.2)分、(2.5±1.4)分、(2.3±1.1)分、(2.4±1.9)分、(2.5±1.3)分.术前患者ODI为(55.0±6.0)%,术后1 d、3 d、1周、1个月、6个月ODI分别为(15.0±6.0)%、(13.0±4.0)%,(12.0±3.0)%,(13.0±6.0)%,(14.0±5.0)%.与术前比较,术后各时点患者VAS评分、ODI均显著降低(均P〈0.05);而术后各时点患者的VAS评分、ODI比较,差异均无统计学意义(均P〉0.05).结论 背根神经节脉冲射频联合复方倍他米松注射治疗老年退行性腰椎管狭窄症疗效较好. Objective To investigate the clinical effect of dorsal root ganglion pulsed radiofrequency combined with compound betamethasone injection in the treatment of senile degenerative lumbar spinal stenosis. Methods Eighteen patients with senile degenerative lumbar spinal stenosis,who underwent ineffective conservative treatment and registered in our department between December 2014 and June 2015,were included in this study. All the patients underwent dorsal root ganglion pulsed radiofrequency combined with compound betamethasone injection. The visual analogue scale (VAS) and Oswestry dysfunction index(ODI)were recorded and compared at baseline and at 1 d,3 d,1 week,1 month,and 6 months after the treatment. Results Eighteen patients underwent the operation successfully,and there were no intraoperative and postoperative complications. The VAS score at baseline and at 1 d,3 d,1 week,1 month,and 6 months after the treatment were 6.5 ± 0.7,2.7 ± 1.2,2.5 ± 1.4,2.3 ± 1.1,2.4 ± 1.9 and 2.5 ± 1.3, respectively. The ODI at baseline and at 1 d,3 d,1 week,1 month,and 6 months after the treatment were (55.0 ± 6.0)%,(15.0 ± 6.0)%,(13.0 ± 4.0)%,(12.0 ± 3.0)%,(13.0 ± 6.0)%,and (14.0 ± 5.0)%, respectively. The VAS scores and ODI were significantly decreased at all the time points after treatment as compared with those at baseline(all P〈0.05);whereas,there were no statistically significant differences in the VAS scores and ODI at all the time points after treatment(all P〉0.05). Conclusion The effect of dorsal root ganglion pulsed radiofrequency combined with compound betamethasone injection is good in the treatment of senile degenerative lumbar spinal stenosis.
出处 《中华生物医学工程杂志》 CAS 2017年第1期46-50,共5页 Chinese Journal of Biomedical Engineering
关键词 腰椎管狭窄症 背根神经节 脉冲射频 倍他米松 Lumbar spinal stenosis Dorsal root ganglion Pulsed radiofrequency Betamethasone
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  • 1肖礼祖,熊东林,蒋劲,张强,郑虎山,辜树蓉.脉冲射频治疗腰骶部神经根性疼痛的疗效观察[J].中国微侵袭神经外科杂志,2004,9(11):489-490. 被引量:9
  • 2彭岚,卢振和,高崇荣.脊神经脉冲射频治疗神经根性腰腿痛参数的临床研究[J].广东医学,2007,28(9):1483-1485. 被引量:13
  • 3Ramanavarapu V,Simopoulos TT.Pulsed radiofrequency of lumbar dorsal root ganglia for chronic post-amputation stump pain.Pain Physician,2008,11(4):561-566.
  • 4Rozen D,Ahn J.Pulsed radiofrequeney for the treatment of ilioinguinal neuralgia after inguinal hemiorrhaphy.Mt Sinai J Med,2006,73(4):716-718.
  • 5Erdine S,Yucel A,Cimen A,et al.Effects of pulsed versus conventional radiofrequency current on rabbit dorsal root ganglion morphology.Eur J Pain,2005,9(3):251-256.
  • 6Onozawa T, Atsuta Y, Sato M, et al. Nitric oxide induced ectopic firing in a lumbar nerve root with cauda equina compression. Clin Ortbop,2003, (408) :167 - 173.
  • 7Porehet K, Weitlisbach V, Burrand B, et al. Relationship between severity of lumbar disc disease and disability scores in sciatica patients. Neurosurgery,2002,50 (6) : 1253 - 1259.
  • 8Van Boxem K, van Bilsen J, de Meij N, et al. Pulsed radiofrequency treatment adjacent to the lumbar dorsal root ganglion for the management of lumbosacral radicular syndrome: a clinical audit. Pain Med,2011,12(9) :1322 - 1330.
  • 9Thoomes EJ,Schohen-Peeters W, Koes B, et al. The effectiveness of conservative treatment for patients with cervical radiculopathy: a systematic review. Clin J Pain. 2013,29(12) :1073 -1086.
  • 10Park HW,Ahn SH, Son JY, et al. Pulsed radiofrequency application reduced mechanical hypersensitivity and microglial expression in neuropathic pain model. Pain Med ,2012,13 (9) : 1227 - 1234.

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