摘要
目的:研究九节根的化学成分。方法:九节根用80%乙醇回流提取,提取液经减压浓缩得到浸膏,水部位应用D101大孔树脂、硅胶柱层析、ODS C18和Sephadex LH-20柱色谱分离得到8个化合物,并根据其理化性质和波谱分析来解析这些化合物的结构。结果:从九节根中分离得到8个化合物,分别鉴定为:asperulosidic acid(1)、6-methoxygeniposidic acid(2)、6α-hydroxygeniposide(3)、deacetylasperulosidic acid(4)、asperuloside(5)、蔗糖(6)、蔗糖乙酸酯(7)、葡萄糖乙酸酯(8)。结论:化合物1、2、4、5为首次从该植物中分离得到,化合物2、4为首次从该属植物中分离得到。
Objective : To study the chemical constituents from the roots of Psychotria rubra. Methods : The roots of Psychotria rubra were extracted with 80% ethanol for reflux, and the extracts were evaporated. Eight compounds were isolated by D101 macroporous resin, silica gel chromatography, ODS C18 and Sephadex LH-20 column chromatography from water part of extracts. Their structures were i- dentified on the basis of physico-chemical characters and spectroscopic analysis. Results : Eight compounds were obtained from the roots from Psychotria rubra, and identified as asperulosidic acid ( 1 ) ,6-methoxygeniposidic acid (2) ,6α-hydroxygeniposide (3), deacetylaspe- mlosidic acid (4), asperuloside ( 5 ) , sucrose ( 6 ), 1-O-acetyl-β-D-galactopyranose ( 7 ) and 1-O-acetyl-β-D-glucoside ( 8 ). Conclusion: Compounds 1,2,4,5 are isolated from Psychotria rubra for the first time, compounds 2,4 are isolated from Psychotria genus for the first time.
出处
《中药材》
CAS
北大核心
2017年第4期858-860,共3页
Journal of Chinese Medicinal Materials
基金
广西自然科学基金项目(2015GXNSFAA139103)
广西植物功能物质研究与利用重点实验室开放基金(FPRU2013-5)
关键词
九节
化学成分
结构鉴定
Psychotria rubra ( Lour. ) Poir.
Chemical constituents
Structure identification