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MicroRNA在动脉粥样硬化中的研究进展 被引量:2

The recent progress of microRNA in the process of atherosclerosis
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摘要 机体是由数以亿万计分子量大小不等的分子组成.蛋白质和核酸是体内主要的大分子.核酸以核苷酸为基本组成单位,分为脱氧核糖核酸(deoxyribonncleic acid,DNA)和核糖核酸(ribonucleic acid,RNA)两类.DNA存在于细胞核和线粒体内,携带遗传信息.遗传信息的表达(即基因表达)就是将储存于DNA中的信息通过转录的过程传递到RNA分子中,再通过翻译过程将RNA分子上的核苷酸序列信息转变为蛋白质分子中的氨基酸序列,因此,RNA是DNA的转录产物,参与遗传信息的复制和表达.RNA存在于细胞质、细胞核和线粒体内,同时也可作为遗传信息的载体.
出处 《中国心血管病研究》 CAS 2017年第9期769-773,共5页 Chinese Journal of Cardiovascular Research
基金 山东省中医药科技发展计划重点专项课题(项目编号:2013ZDZK-105)
关键词 动脉粥样硬化 MICRORNA 内皮细胞 单核/巨噬细胞 平滑肌细胞 Atherosclerosis MicroRNA Endothelial cells Monocytes/Macrophages Smooth muscle cells
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