胸痛患者腰围甘油三酯指数与代谢综合征相关性的研究

Relationship between waist circumference-triglyceride index and metabolic syndrome in chest pain patients

目的 研究胸痛患者腰围甘油三酯（WT）指数与代谢综合征（MS）的关系.方法 回顾性分析在我院就诊的胸痛患者.比较MS组和非MS组基线资料的差异,分析WT指数与代谢综合征的相关性.结果 共有309例患者入选,其中女性115例,MS的检出率为71.1％.MS组的体重、腰围、低密度脂蛋白胆固醇、甘油三酯、空腹血糖、体重指数和WT指数[分别为（75.3±11.4）kg、（97.1±9.3）cm、（2.85±0.93）mmol/L、（2.11±1.13）mmol/L、（6.56±2.29）mmol/L、（26.6±3.3）kg/m2和（205.5±113.5）]均高于非MS组[分别为（65.5±8.9）kg、（88.0±8.5）cm、（2.62 ±0.84）mmol/L、（1.25±0.53）mmol/L、（5.42±1.14）mmol/L、（24.4 ±3.1）kg/mz和（205.5±113.5）]（均P＜0.05）,高密度脂蛋白胆固醇低于非MS组[（1.02±0.27）mmol/L比（1.33-±0.66）mmol/L,P＜0.05].多因素Logistic回归表明,WT指数是代谢综合征的独立预测因素（OR=1.075,95％CI 1.028～1.124）.WT指数在全部研究人群、男性人群及女性人群ROC曲线下面积分别为0.839（95％CI 0.793～0.878）、0.877（95％CI0.803～0.931）和0.858（95％CI 0.801～0.904）;其预测心血管危险因素聚集的最佳切点分别为143.0、142.0和139.1.结论 WT指数是胸痛患者代谢综合征的独立预测因素,适合于基层医疗机构对高危心血管病人群进行筛查.

Objective To study the relationship between waist circumference-triglyceride（WT） index and metabolic syndrome （MS） in chest pain patients.Methods This was a retrospective cohort study.Chest pain patients admitted to our hospital from April 2014 to December 2015 were enrolled.The basic characteristic differences between MS group and non-MS group were analyzed.The relationship WT index and MS was analyzed by Pearson relationship analysis and logistic regression analysis.Results A total of 309 patients were enrolled,115 of them were female.The prevalence of MS was 71.1%.Levels of weight,waist circumference,low-density lipoprotein cholesterol,triglyceride,fasting blood glucose,body mass index,and WT index in MS group were higher than that in non-MS group [（75.3±11.4）kg vs （65.5±8.9）kg,（97.1±9.3）cm vs （88.0±8.5）cm,（2.85±0.93）mmol/L vs （2.62±0.84）mmol/L,（2.11±l.13）mmol/L vs （1.25±0.53）mool/L,（6.56±2.29）mmol/L vs （5.42±1.14）mmol/L,（26.6±3.3）kg/m2 vs （24.4±3.1）kg/m2,and （205.5±113.5） vs （205.5±113.5）,all P〈0.05].The level of high-density lipoprotein cholesterol in non-MS group was lower [（1.02±0.27）mmol/L vs （1.33±0.66）mmol/L,P〈0.05].WT index was an independent risk factor of MS by multivariate logistic regression analysis （OR=1.075,95%CI 1.028-1.124）.The receiver operating characteristic curves of WT index in total patients,male patients,and female patients were 0.839 （95%CI 0.793-0.878）,0.877 （95%CI 0.803-0.931） and 0.858（95%CI 0.801-0.904）,respectively;and the cutoff values of WT index were 143.0,142.0 and 139.1,respectively.Conclusion WT index is an independent risk factor of MS and could be applicable for screening high risk cardiovascular patients in primary health care institution.