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血栓抽吸前后冠脉注射替罗非班对STEMI行PCI术后预后的影响 被引量:1

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摘要 目的:探讨急性ST段抬高型心肌梗死患者(STEMI)行急诊经皮冠脉介入(PCI)术中血栓抽吸前后冠脉注射替罗非班对预后的影响。方法:选取我院2015年3月-2017年1月收治的180例STEMI,均进行PCI术治疗。随机分为三组,各60例。A组在行血栓抽吸前通过抽吸导管冠脉内注入替罗非班,后进行常规PCI并植入支架;B组抽吸后经冠脉内注入替罗非班;C组在抽吸前后分别经冠脉内注入替罗非班;比较术后临床效果及心血管事件发生率。结果:临床效果主要指标为ST段回落、心肌梗死溶栓实验(TIMI)血流分级、心功能;心血管事件主要指标为梗死再发、支架内血栓再形成、血运重建、心衰加重等。A组与B组术后以上指标差异无统计学意义(P>0.05)。C组术后临床指标改善优于A、B两组(P<0.05),心血管事件发生率与A、B组比较差异无统计学意义(P>0.05)。结论:STEMI行PCI术中血栓抽吸前后冠脉注射替罗非班能够更有效改善患者心功能及心肌微循环,并且不会增加心血管事件发生,提高围术期安全。
出处 《医学理论与实践》 2017年第22期3324-3326,共3页 The Journal of Medical Theory and Practice
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