自拟益气扶阳汤用于慢性乙型病毒性肝炎的疗效观察

Observation on Efficacy of Self-prescription of Yiqi Fuyang Decoction in Treatment of Chronic Viral Hepatitis B

目的:探讨自拟益气扶阳汤用于慢性乙型病毒性肝炎的临床疗效,为临床用药提供参考。方法:选取2013—2016年赣州市南康区中医院收治的慢性乙型病毒性肝炎患者100例,采用随机数字表法分为对照组和观察组,每组50例。对照组患者给予常规西药治疗,观察组患者在对照组基础上给予自拟益气扶阳汤,观察两组患者的临床疗效及治疗前后肝功能情况。结果:观察组患者的总有效率为94.00%(47/50),明显高于对照组的80.00%(40/50),差异有统计学意义(P<0.05);经过3个月的治疗,两组患者的丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、γ-谷酰转肽酶及总胆红素水平较治疗前明显降低,且观察组患者各项指标水平明显低于对照组,差异均有统计学意义(P<0.05)。结论:在常规西药基础上加用自拟益气扶阳汤治疗慢性乙型病毒性肝炎,效果显著,能明显改善患者的肝功能。

OBJECTIVE：To probe into the clinical efficacy of self-prescription of Yiqi Fuyang decoction in treatment of chronic viral hepatitis B , so as to provide references for clinical medication .METHODS：100 patients with chronic viral hepatitis B admitted into Ganzhou Nankang Hospital of TCM during 2013-2016 were selected and divided into control group and observation group via random number table , with 50 cases in each group .The control group was given conventional therapy with western medicine , while the observation group was treated with self-prescription of Yiqi Fuyang decoction based on the control group .Clinical efficacy and hepatic function of before and after treatment of two groups were observed .RESULTS：The total effective rate of observation group （94.00%, 47/50） was significantly higher than that of the control group （ 80.00%, 40/50 ） , with statistically significant difference （ P 〈0.05 ）; after a 3-month treatment , levels of alanine aminotransferase , aspartate aminotransferase , gamma-glutamyl transpeptidase and total bilirubin of both groups had been significantly decreased , and those of the observation group was significantly lower than the control group, with statistically significant differences （P〈0.05）.CONCLUSIONS：The efficacy of self-prescription of Yiqi Fuyang decoction combined with conventional therapy in treatment of chronic viral hepatitis B is remarkable , which can significantly improve the hepatic function for patients .