下呼吸道感染病原菌检出率及耐药性探究

Detection rate and drug resistance of pathogenic bacteria in lower respiratory tract infection

目的:探究下呼吸道感染患者痰标本病原菌分布和耐药性。方法:收治下呼吸道感染患者1 054例。采集患者痰标本,进行病原菌耐药性回顾分析。结果:病原菌检出率13.5%。其中主要为革兰阴性杆菌,革兰阳性球菌以肺炎链球菌为主。药敏结果显示下呼吸道病原菌对抗生素的药物敏感性各不相同,具有各自的耐药特点。结论:下呼吸道病原菌对抗生素的耐药性较强,应规范抗生素在下呼吸道疾病治疗中的使用,防止病原菌耐药性变异。

Objective:To investigate the distribution and drug resistance of pathogenic bacteria in sputum samples of lower respiratory tract infection patients.Methods:1 054 cases of lower respiratory tract infection were selected,and the sputum samples were analyzed retrospectively.Results:The detection rate of pathogens was 13.5%,in which the gram negative bacilli were the most common,and gram positive cocci were mainly streptococcus pneumoniae.Susceptibility tests showed that lower respiratory tract pathogens were sensitive to antibiotics,and each had its own resistance characteristics.Conclusion:Lower respiratory tract pathogens have strong antibiotic resistance,and antibiotics should be standardized in the treatment of lower respiratory tract diseases,so as to prevent drug resistance of pathogens.