神经保护剂治疗急性脑梗死患者的效果及安全性观察

Efficacy and safety of neuroprotective agents in the treatment of acute cerebral infarction

目的:研究并探讨神经保护剂治疗急性脑梗死患者的临床效果和安全性。方法:收治急性脑梗死患者120例,随机平分两组。对照组采取常规方案进行治疗,观察组在此基础上给予神经保护剂治疗。治疗2周后,对两组临床疗效、神经功能缺损评分、日常生活能力评分、不良反应发生率等方面进行比较。结果:观察组总有效率明显高于对照组(P<0.05);治疗后两组神经功能缺损评分、日常生活能力评分均较治疗前显著改善(P<0.05),但治疗后,观察组的神经功能缺损评分低于对照组(P<0.05),日常生活能力评分高于对照组(P<0.05)。结论:在急性脑梗死患者临床治疗中应用神经保护剂进行治疗,不仅具有显著的临床效果,还具有可靠的安全性。

Objective:To study and explore the clinical efficacy and safety of neuroprotective agents in the treatment of acute cerebral infarction.Methods:120 patients with acute cerebral infarction were selected.They were randomly divided into the two groups on average.The control group received routine treatment,and the observation group was given neuroprotective treatment on the basis of this.After 2 weeks of treatment,the two groups were compared in clinical efficacy,neurological impairment score,daily living ability score,incidence of adverse reactions.Results:The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).The neurological deficits scores and daily living ability scores of the two groups were significantly improved compared with those before treatment(P<0.05).After treatment,the neurological impairment score of the observation group was lower than that of the control group(P<0.05),and the scores of daily living ability were higher than those of the control group(P<0.05).Conclusion:The use of neuroprotective agents in the treatment of patients with acute cerebral infarction has not only a significant clinical effect,but also a reliable safety.