结直肠癌患者手术部位感染相关因素分析

Analysis of risk factors of surgical site infection in patients with colorectal cancer

目的 探讨结直肠癌患者手术部位感染的相关因素.方法 回顾性分析结直肠癌患者542例的临床资料,根据手术部位是否感染将患者分为感染组（n=48）和非感染组（n =494）,分析其手术部位感染的危险因素.结果 与非感染组比较,感染组患者年龄显著增加[（67.74±9.46）岁比（57.63±9.94）岁,t=7.593,P=0.000）],糖尿病患病率显著增高（25.00％比8.70％,x^2=12.843,P=0.000）,开腹手术率显著增加（70.83％比33.81％,x^2=25.946,P=0.000）,手术时间显著延长[（123.45±23.56） min比（110.47±19.47） min,t=10.485,P=0.000）].Logistic回归分析显示年龄、糖尿病、开腹手术和手术时间是手术部位感染的危险因素（P＜0.05）.结论 年龄、糖尿病、开腹手术和手术时间是结直肠癌患者手术部位感染的独立危险因素.

Objective To investigate the risk factors of surgical site infection in patients with colorectal cancer.Methods Clinical data of 542 patients with colorectal cancer were retrospectively studied.According to the infection of surgical site or not,all patients were assigned into infection group （n =48） or non-infection group （n =494）.The risk factors of surgical site infection were analyzed.Results Compared with non-infection group,the patients in the infection group got significant increase in age [（67.74 ± 9.46） years vs.（57.63 ± 9.94） years,t =7.593,P =0.000],significantly higher rate of diabetes （25.00% vs.8.70%,x^2 =12.843,P =0.000）,significantly x higher rate of open surgery （70.83% vs.33.81%,x^2 =25.946,P =0.000）,and significantly longer operation duration [（123.45 ± 23.56） min vs.（110.47 ± 19.47） min,t =10.485,P =0.000].Logistic study showed that age,diabetes,open surgery and operation duration were risk factors for the development of surgical site infection （all P 〈 0.05）.Conclusion Age,diabetes,open surgery and operation duration are risk factors for the development of surgical site infection in colorectal cancer.