声触诊组织定量技术检测胰腺弹性评估2型糖尿病微血管并发症的临床价值

Value of pancreatic elastography by virtual touch tissue quantification in evaluating type 2 diabetic microangiopathy

目的探讨声触诊组织定量技术测量胰腺组织剪切波速度(SWV)以评估2型糖尿病微血管并发症的可行性。方法应用声触诊组织定量技术分别检测2型糖尿病患者有微血管并发症组(47例)、无微血管并发症组(68例)及正常对照组(115例)受检者的胰腺头、体及尾部SWV值,比较各组胰腺各部位SWV值的差异;探讨影响2型糖尿病患者胰体SWV值的相关因素。结果有微血管并发症组和无微血管并发症组胰腺头、体及尾部SWV值均明显高于正常对照组,差异均有统计学意义(均P<0.01);有微血管并发症组胰体SWV值为(1.35±0.16)m/s,明显高于无微血管并发症组(1.26±0.11)m/s,差异有统计学意义(P<0.01)。2型糖尿病患者的胰体SWV值与微血管并发症、年龄及总胆固醇呈正相关(P=0.022、0.004、0.011)。结论 2型糖尿病患者胰体SWV值与微血管并发症相关,胰体SWV值在评估糖尿病微血管并发症中有一定的临床价值。

Objective To investigate the feasibility of pancreatic shear wave velocity（SWV） in evaluating type 2 diabetic microangiopathy.Methods Forty-seven cases of type 2 diabetic patients with microangiopathy and 68 cases of type 2 diabetic patients without microangiopathy were enrolled in this study,and 115 health volunteers were taken as control group.The SWV value of pancreatic head,body and tail in those three groups were measured by virtual touch tissue quantification technology,the results among three groups were compared.Factors that were associated with the value of SWV of pancreatic body were also studied in type 2 diabetic patients. Results The SWV value of pancreatic head,body and tail increased in type 2 diabetic groups were higher than those in control group（all P〈0.01）.The SWV value of pancreatic body in microangiopathy group and without microangiopathy group were（1.35±0.16）m/s and（1.26±0.11）m/s,there was significant difference（P〈0.01）.In type 2 diabetic patients,microangiopathy,age and total cholesterol levels were positively correlated with SWV value of pancreatic body（P = 0. 022,0.004,0.011）.Conclusion SWV of pancreatic body is related to the presence of microangiopathy.SWV value of pancreatic body had a certain value in evaluating type 2 diabetic microangiopathy.