甘肃地区1120例白癜风患者的临床特点及疗效分析

Analyse Clinical Features and Curative Effect of 1120 Cases of Patients with Vitiligo

目的:总结分析甘肃地区1 120例白癜风患者的临床特点和治疗效果,为制定防治措施提供依据。方法:采用问卷调查的形式对确诊的白癜风患者进行临床研究,用SPSS19.0软件包进行统计分析。结果:1 120例白癜风患者中,男550例,女570例;平均发病年龄(20.04±14.16)岁,发病高峰17~21岁;患者职业中学生最多418例(37.72%);571例(50.98%)的皮损累及头颈部;1级(轻度)白癜风患者658例(58.75%),进展期患者比稳定期多;423例(37.77%)在春夏季发病,526例(46.96%)有诱发因素;134例患者有家族史,伴发疾病中以甲状腺疾病最常见(78例);在各型白癜风中未定类型(局限型)疗效最佳。治疗6个月后痊愈23例(18.25%),显效41例(32.54%),总有效率50.79%。结论:本地区白癜风好发于青少年,男女发病比例相近,最常累及部位是面颈部,精神心理因素为常见诱因,伴发率最高的疾病为甲状腺疾病,临床疗效有待提高。

Objective To summarize and analyze the clinical features and therapeutic effcacy of 1120 cases of patients with vitiligo,and provide evidence for the prevention and control of the disease. Methods The clinical investigation of vitiligo patients was carried out in the form of questionnaire, and the SPSS 19 software package was used for statistical analysis. Results Of the 1120 patients, 550 are males and 570 are females,with the average age of 20.04±14.16 years, 17-21 years are the peak period of incidence. Most patients are students, 418 cases （37.72%）. 571 cases （50.98%） of the lesions involved the head and neck. 658 cases of patients （58.75%）with vitiligo was in Grade 1（mild）,patients in progressive stage are more than the ones in stable stage; 423 cases（37.77%） happened in the spring and summer, 526 cases （46.96%） had induced factors; 134 patients had family history, the most common associated diseases was thyroid disease （78 cases）. And the curative effect of localized type was the best. After 6 months of treatment, 23 cases （18.25%） was recovered, 41 cases were markedly effective （32.54%）, the total effciency was 50.79%. Conclusion Most vitiligo occurred in adolescents. the incidence of men and women was alike, the most frequently involved sites were neck and neck, mental and psychological factors were common causes, the most common associated diseases was thyroid disease, the highest incidence of thyroid disease is the disease, The curative effect remains to be improved.