摘要
目的:通过回顾性分析急性主动脉综合征(AAS)合并弥漫性血管内凝血(DIC)患者诊断、治疗及预后。方法:回顾性分析大连医科大学附属第一医院2013-05-2017-05收治的232例AAS住院患者的临床资料。其中全部入选患者根据其是否合并DIC分为AAS合并DIC组(AAS-DIC组)和AAS未合并DIC组(AAS组),比较两组之间临床特点的差异。结果:对于入组的232例AAS患者中,合并DIC共有19例(8.2%),患者预后不佳。其中10例入院时确诊DIC患者中,5例行外科手术治疗,3例死亡;5例保守治疗患者全部死亡。9例外科术后合并DIC患者中,5例死亡。AAS组及AAS-DIC组DIC筛选指标均存在显著性差异,对于外科手术术后合并DIC组,引流量存在及ICU滞留时间存在显著差异,但体外循环手术时间及停止循环时间方面均无明显差异。结论:AAS易导致DIC的发生,外科手术治疗对于救治AAS合并DIC患者虽然有效,但不能显著改善该类患者的预后。
Objective:To retrospectively analyze the diagnosis,treatment and prognosis of patients with acute aortic syndrome(AAS)complicated with disseminated intravascular coagulation(DIC).Method:The clinical data of232 patients with AAS admitted to the First Affiliated Hospital of Dalian Medical University from May 2013 to May 2017 were analyzed retrospectively.All the patients were divided into AAS-DIC group and AAS group according to whether or not they suffered from DIC.The clinical characteristics of the two groups were compared.Result:The 232 patients with AAS were enrolled in our research.There were 19 patients(8.2%)with DIC,and the prognosis of them was poor.Among them,10 patients were diagnosed with DIC at the time of admission.In the 10 cases,3 of 5 patients died underwent surgical treatment,another 5 patients also died after nonoperative treatment.Of the 19 cases with DIC,9 patients were diagnosed with DIC after surgery,5 of 9 patients died.Between AAS group and AAS-DIC group,there was significant difference in the ICU retention time and the existing drainage,but not in cardiopulmonary bypass operation time and cycle time.Conclusion:AAS is prone to DIC and the surgical treatment for AAS patients with DIC is effective,but does not significantly improve the prognosis of these patients.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2017年第11期1083-1086,共4页
Journal of Clinical Cardiology
关键词
急性主动脉综合征
弥漫性血管内凝血
心脏外科手术
acute aortic syndrome ldisseminated intravascular coagulation
cardic surgical procedures