摘要
精准药物治疗是精准医学的重要内容,是基于患者个体特征制定治疗方案的个性化医疗模式。肾脏疾病种类繁多,发病机制复杂,患者个体差异大,精准治疗尤为重要。肾脏疾病精准治疗的目标是研究发现与治疗相关的生物标志物,以及通过药物相关基因或特定目标基因进行治疗干预。目前,肾脏疾病精准药物治疗在生物标志物、药物遗传学等方面取得了一定进展,本文主要就相关研究进展进行综述。
Precision drug therapy is an important part of precision medicine, which emphasizes personalized medical model based on patients＇ individual characteristics. There are many types of kidney diseases, with complex pathogenesis and large individual differences. Precision therapy is particularly important. The goal of precision therapy of renal disease is to identify biomarkers related to therapy, and give therapeutic intervention through drugs related genes or specific target genes. At present, precision drug therapy of kidney diseases has made some progress in biomarkers, pharmacogenetics and other aspects. This paper reviewed the progress of these studies.
出处
《临床药物治疗杂志》
2017年第9期1-5,共5页
Clinical Medication Journal
基金
北京大学第三医院临床重点项目<基于尿磷脂谱的药源性肾脏损伤早期诊断技术的研究>(BYSY2015012)
