中药代谢组学临床治疗研究的文献计量分析

Bibliometric analysis of the metabolomics of traditional Chinese medicine clinical treatment

目的:在Web of Science数据库中计量分析中药代谢组学领域的文献,为了解中药代谢组学的临床治疗研究现状提供参考。方法:在Web of Science数据库中进行检索,以"metabolomics or metabonomics"和"traditional Chinese medicine"为主题词检索,利用数据库提供的出版年、研究方向、国家/地区、机构、作者和来源出版物等条件进行分析,并分析文献引用情况。结果:获得结果 429条,文章发表量与引文数逐年递增;chemistry是该领域目前研究最多的方向;中国以世界文章发表量的92.308%名列首位。排名前10的机构均来自中国;其中,黑龙江中医药大学(12.821%)、中国科学院(10.490%)和中国药科大学(6.527%)文章发表最多。结论:中药代谢组学在临床诊断、治疗中具有重要作用,中国在中药代谢组学研究方面领先世界,美国和英国等发达国家在此方面也逐渐加深重视,但与中国还存在一定差距。

Objective： To understand the current research status of metabolomics of traditional Chinese medicine, a Web of Science based bibliometric analysis was carried out. Methods： The ＂metabolomics or metabonomics＂ and ＂traditional Chinese medicine＂ were chosen as terms in literature searching in Web of Science citation database（2005―2017）. The results were analyzed with regard to the number of articles, research sub-field, total citations, country/area, institutes, authors, journal of publication and so on. The citation analysis was done automatically by the database. Results： 429 literatures concerning metabolomics and traditional Chinese medicine were recorded in Web of Science. The total number of publications and citations keep increasing in this field. The chemistry was the hottest and the most important sub-field in metabolomics of traditional Chinese medicine research. China had the largest number of publications; it occupied 92.308% of the total amount of the published articles. The top ten institutions with the most article publication was from China. In China, Heilongjiang University of Chinese Medicine（12.821%）, Chinese Academy of Sciences（10.490%） and China Pharmaceutical University（6.527%） were the top 3 institutions having the highest number of publication. Conclusion： Metabolomics of traditional Chinese medicine is flourishing, China leads the world, followed by the United States and England and other developed countries, but there are a certain gap between the United States and China.