胰腺神经内分泌肿瘤的CT表现及其诊断价值分析

CT manifestations of pancreatic neuroendocrine tumors and analysis of their diagnostic value

目的探讨胰腺神经内分泌肿瘤(NETP)的CT影像学特征及其诊断价值。方法选取2010年2月~2015年6月在我院治疗的胰腺神经内分泌肿瘤(NETP)患者32例,所有患者行CT平扫及动态增强扫描,分析各病理分级患者CT表现。结果术前CT诊断符合率为84.38(27/32),误诊5例,其中2例误诊为胰腺癌,1例误诊为腹膜后间质源性肿瘤,1例误诊为胰腺囊腺癌;病理分级为2级的患者动脉期、静脉期和平衡期绝对强化程度分别为(110.30±32.83)HU、(83.93±17.59)HU和(79.29±18.96)HU,明显高于病理1级和3级患者(P<0.05);病理分级为3级患者动脉期、静脉期和平衡期绝对强化程度最低;病理分级为2级的患者动脉期、静脉期和平衡期相对强化程度分别为(50.32±16.93)HU、(35.10±11.23)HU和(28.43±9.03)HU,明显高于病理1级和3级患者(P<0.05);病理分级为3级患者动脉期、静脉期和平衡期相对强化程度最低。结论胰腺神经内分泌肿瘤的CT表现有一定的特点,CT检查有助于胰腺神经内分泌肿瘤的评价和临床治疗方案的制定。

Objective To investigate CT manifestations of pancreatic neuroendocrine tumors and to analyze their value in thie diagnosis of this disorder. Methods From February 2015 to June 2010, 32 patients with pancreatic neuroendocrine tumor （NETP） were selected, who were treated in our hospital. All patients underwent CT scan and enhanced dynamic contrast-en- hanced scan. Results The preoperative coincidence rate with CT diagnosis was 84.38% （27/32） , and 5 patients were misdiag- nosed, in whom 2 patients were misdiagnosed as pancreatic carcinoma, 1 patient was misdiagnosed as retroperitoneal stromal tumors, and 1 patient was misdiagnosis as pancreatic cystadenocarcinoma. In patients with pathological grade II, the absolute en- hancement degree at arterial phase, venous phase, and equilibrium phase were （110.30 ± 32.83） HU, （83.93 ±17.59） HU and （79.29 ± 18.96） HU, which were significantly higher than those in patients with the pathological grade I and III （ P 〈 0. 05 ）. The absolute enhancement degree in patients with pathological grade III at the arterial phase, venous phase and equilibri- um phase was the lowest. The relative enhancement degree in patients with pathological grade II at the arterial phase, venous phase and equilibrium phase were （50.32 ± 16.93 ） HU, （ 3.51 ± 11.23 ） HU and （28.43 ± 9.03 ） HU, which were significant- ly higher than those in patients with the pathological grade I and III（ P 〈 0.05 ） ; The relative enhancement degree in patients with the pathological III at the arterial phase, venous phase and equilibrium phase was the lowest. Conclusion CT findings of pancreatic neuroendocrine tumors have certain characteristics, CT examination can be helpful for the evaluation of pancreatic neu- roendocrine tumors and the formulation of clinical treatment regimens.