不同厂家首乌藤配方颗粒质量比较

Quality Comparative Analysis of Polygoni Multiflori Caulisformula Granule with Different Manufacturers

目的:对不同厂家首乌藤配方颗粒的质量进行分析比较。方法:按照2015年版《中国药典》四部颗粒剂要求对5个不同厂家的首乌藤配方颗粒进行性状、水分、粒度、溶化性、鉴别、装量、药物吸湿性、浸出物、含量的考察。结果:5个厂家样品性状、水分、粒度、溶化性、鉴别、装量均符合规定,但不同厂家样品的吸湿性、浸出物、含量差异较大。结论:不同厂家的首乌藤配方颗粒质量存在较大差异,临床用药时需加以注意。

Objective. Quality comparative of Polygoni Multiflori Caulis formula granule with different manufacturers. Methods. Accordance with the＂Chinese Pharmacopoeia＂2015 quality standards for five different manufacturers character, particle size, moisture, dissolubility, identification, weight, drug induced moisture, extraction and content, examining its quality. Results ： All in compli- ance with the provisions of character, particle size, moisture, dissolubility, identification and weight, but different manufacturers of drug induced moisture,extraction and content high and low. Conclusion： Different manufacturers of Polygoni Multiflori Caulis formula granule quality arebig gap,which provide the basis for clinical medication safety.