中药外洗治疗湿疹200例临床疗效观察

Clinical observation on treating 200 cases of eczema by external washing with TCM medicine

目的:观察中药止痒洗剂外洗治疗200例湿疹患者的临床疗效。方法:采用随机数字表法将200例急性、亚急性湿疹的患者随机分为治疗组和对照组;其中治疗组100例,每日用中药止痒洗剂(苦参、蛇床子、地肤子、百部、花椒、薄荷、紫草等)煎水外洗治疗配合西药西替利嗪片每日1片口服,同时曲安奈德霜外用;对照组100例患者单用西替利嗪片每日1片口服加曲安奈德霜外用,治疗2周前后分别观察两组患者湿疹面积的EASI积分变化以及瘙痒积分变化,同时记录两组患者止痒起效时间及止痒持续时间的变化,分别观察两组患者的治疗效果及止痒效果。结果:2周治疗结束后,治疗组与对照组临床总有效率观察,治疗组总有效率95%,对照组总有效率86%,两组临床总有效率比较(P>0.05),其差异无显著性意义;两组患者治疗前后组内瘙痒积分比较(P<0.05);两组患者治疗后止痒起效时间、止痒持续时间比较,治疗组在止痒起效时间与止痒持续时间比较上明显优于对照组(P<0.05)。结论:中药外洗治疗湿疹临床疗效确切,在止痒起效时间以及止痒持续时间上明显优于单用西药治疗,值得临床推广使用。

Objective： To observe the clinical efficacy of TCM medicine anti-pruritic lotion on 200 cases of eczema. Methods： 200 patients with acute and subacute eczema were randomly divided into the treatment group （100 cases） and the control group （100 cases）. The treatment group was treated daily with TCM medicine anti-pruritic lotion （Sophora flavescens, Cnidium, Kochia, Stemona, pepper, mint, Lithospermum） and western medicine, including one Cetirizine tablet daily and Triamcinolone acetonide cream for external use, while the control group only took the tablets and apply the cream. The changes of eczema area, itching score, itching onset time and itching duration, and antipruritic were observed and recorded. Results： In 2 weeks, the total efficiency in the treatment group turned out to be 95%; and that in the control group was 86%. There was no significant difference （P〉0.05） between groups in the total efficiency. The difference in the itching score in groups was significant （P〈0.05）. The treatment group was superior to the control group in action time and antipruritic- duration. Conclusion： The external washing with TCM medicine was effective on eczema, significantly superior to western medicine in action time and antipruritic- duration, and is worthy of clinical application and promotion.