胃苏颗粒联合多潘立酮治疗肝胃气滞型慢性胃炎30例的临床观察

Observation on treating chronic gastritis of the Ganwei Qizhi type with the Weisu granules plus domperidone

目的:研究胃苏颗粒联合多潘立酮治疗肝胃气滞型慢性胃炎的临床效果。方法:选取2016年8月-2017年8月于我院接受治疗的肝胃气滞型慢性胃炎患者60例作为研究对象,把他们按照随机数表法平均分为两组,其中观察组30例,给予胃苏颗粒联合多潘立酮口服治疗,对照组30例,给予兰索拉唑加多潘立酮口服治疗,对比分析两组患者的治疗效果,临床症状变化情况以及不良反应发生情况。结果:观察组患者在治疗总有效率、临床症状改善情况方面均优于对照组患者,两组患者的对比差异显著(P<0.05),具有统计学意义。在不良反应发生概率方面,两组患者的对比差异无统计学意义(P>0.05)。结论:在治疗肝胃气滞型慢性胃炎方面,使用胃苏颗粒联合多潘立酮对患者进行治疗能够达到更好的治疗效果,显著改善患者的临床症状,患者在接受治疗后的不良反应发生概率比较低,临床治疗效果显著,值得在临床上进行广泛的推广与应用。

Objective： To study the clinical effects of the Weisu granules plus domperidone on chronic gastritis of the Ganwei Qizhi type. Methods： 60 patients with chronic gastritis of the Ganwei Qizhi type who treated in our hospital from August 2016 to August 2017 were divided into two groups according to the random number table. 30 cases were treated with domperidone in the control group. The observation group was treated the Weisu granules plus with domperidone. The therapeutic effects, clinical symptoms, changes of serum gastrointestinal hormone and adverse reactions were compared and analyzed. Results： In the observation group, the treatment efficiency, clinical symptoms improvement and serum gastrointestinal hormone improvement were better than the control group; the difference between groups was statistical significance （P〈0.05）. In the incidence of adverse reaction, there was no significant difference between groups （P〉0.05）. Conclusion： In the treatment of chronic gastritis of the Ganwei Qizhi type, the Weisu granules plus domperidone can achieve a better therapeutic effect, significantly improve the clinical symptoms and serum gastrointestinal hormone level, reduce the incidence of adverse reaction, is worthy of extensive promotion and application in clinical.